Most Five-Factor Model questionnaire items contain unique variance that 1) is heritable, stable, and observable; 2) demonstrates consistent associations with age and sex, and 3) is predictive of life outcomes over and above higher-order factors. This is consistent with items indexing a unique level of the personality trait hierarchy—nuances. Extending these findings to the six-trait HEXACO model, we meta-analyzed cross-rater agreement, heritability, and two-year stability using samples from Canada, Croatia, Finland, Germany, the Netherlands, and the United Kingdom. Analyses were conducted on both raw item scores and their unique variance, and estimates were corrected for short-term test-retest reliability. Median cross-rater agreement, heritability and stability estimates were, respectively, .30,.30 and .57 for raw items and .10,.16 and .39 for item residuals. After reliability correction, the respective medians rose to .46 and .25 for cross-rater agreement, .46 and .39 for heritability, and .87 and 1.00 for stability. These results are strikingly consistent with FFM-based findings, providing further evidence that personality nuances constitute a unique personality hierarchy level with trait properties comparable to those of higher-order traits.