The first experience of using the biocomposite material "Osteomatrix" in the clinic of bone pathology

Introduction. Bone cysts are one of the most common tumor-like bone diseases of childhood, most often occurring in the 1st and 2nd decade of life. According to the world medical literature, there is still no consensus on the best methods of treating bone cysts.Aim – to evaluate the effectiveness of surgical treatment of aneurysmal bone cysts (ABC) in children with the use of allografts of biological (animal and human) origin.Materials and methods. This study included 56 pediatric patients with ABC treated at The National Medical Research Center for Children’s Health, Russia, Moscow. 37 patients with aneurysmal bone cysts (29 active ABC, 8 inactive ABC) underwent surgical treatment. Our follow-up period ranged from 12 months to 80 months. In the postoperative period, the examination was carried out at a period of 3, 6, 12, 18, 24 months and then once a year, while assessing: the presence/absence of the recurrence (radiologically), the timing of functional recovery of the operated segment, the timing of X-ray reconstruction of the graft, the assessment of physical and emotional components of the patients’ quality of life were evaluated using the PedsQL questionnaire at admission and within 12 months from the date of surgery.Results and discussion. In 37 cases of surgical treatment of ABC with the use of allografts of biological origin, the recurrence presented in 7 patients (19%) – these patients, who had an active ABC, required repeated surgical interventions. The average time of complete bone repair in the lesion site ranged from 9 months to 22 months (14 months on average). Functional recovery of the operated segments was on average 10 months for the upper extremities and 12 months for the lower extremities.Conclusion. The use of allografts of biological origin is effective in the case of inactive aneurysmal bone cysts. In case of active ABC the effectiveness of bone grafting with allografts of biological origin is reduced.

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Surgical treatment of aneurysmal bones cysts

Ovechkina

Zherdev

Сhelpachenko

et al. 2022

Medicinskij sovet

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Experience of Surgical Treatment of Tuberculous and Nonspecific Spondylitis with a Barrier Collagen Membrane to Stimulate Osteogenesis in the Site of Bone Block Formation

Peretsmanas,

Bezzubov,

Nikolaev

et al. 2024

Tuberk. bolezni lëgk.

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The objective: to increase effectiveness of surgical treatment of infectious spondylitis with impaired support function of the spinal column through the combined use of a titanium cylindrical block mesh, a resorbable double-sided collagen membrane and an osteoconductor to achieve successful spinal fusion.Subjects and Methods. A prospective monocenter cohort study included 17 patients with infectious spondylitis who were operated with anterior spinal fusion with a titanium mesh graft filled with an osteoconductor and delimited by a barrier double-sided collagen membrane. In the postoperative period, antibacterial treatment was administered based according to the results of bacteriological tests of biological specimensl. Formation of the bone block (spondylodesis) was evaluated by the scale for assessing the fusion of the graft with the bed of the cranial and caudal vertebrae.Results. 6 months after surgery, the fusion of the graft with the bed of the supporting vertebra according to the Baulin scale was 4.5 ± 0.4 scores on the average. In 5 (29%) patients, a clear, homogeneous bone block with a transition of bone beams was achieved after surgery which amounted to 5 scores by the Baulin scale.

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The first experience of using the biocomposite material "Osteomatrix" in the clinic of bone pathology

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Surgical treatment of aneurysmal bones cysts

Surgical treatment of aneurysmal bones cysts

Experience of Surgical Treatment of Tuberculous and Nonspecific Spondylitis with a Barrier Collagen Membrane to Stimulate Osteogenesis in the Site of Bone Block Formation

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