The flora of renal haemodialysis shunt sites.

Rebel, M.; Furth, R. van; Stevens, P.; Bosscher-Zonderman, L; Noble, W. C.

doi:10.1136/jcp.28.1.29

Cited by 15 publications

(3 citation statements)

References 10 publications

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“…Prophylactic parenteral antistaphylococcal therapy reduces overt staphylococcal sepsis but predisposes to Gram-negative infections (Morris and Bilinsky, 1971). The epidemiology of access site infections and their complications has demonstrated that staphylococcal carriage and endogenous infection is the most likely explanation for repeated sepsis (Dobkin et al, 1978;Levi et al, 1970;Martin et al, 1967;McIntosh, Petrie and MacLeod, 1969;Morris and Bilinsky, 1971;Rebel et al, 1975), and most episodes ofsepticaemia in dialysis patients follow shunt or fistula infection. Although eradication of nasal carriage of staphylococci by topical antibiotics does not reduce the incidence of access-site infection (Martin et al, 1967;Morris and Bilinsky, 1971), elimination of skin carriage of staphylococci by hexachlorophane washing reduces the infection rate (Sherrard, 1970).…”

Section: Management Of Infectionmentioning

confidence: 99%

Staphylococcal septicaemia, endocarditis, and osteomyelitis in dialysis and renal transplant patients

Nicholls

Edward

Catto

1980

Postgraduate Medical Journal

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Septicaemia is a common and potentially lethal hazard of haemodialysis and renal transplantation; it is usually caused by Staphylococcus pyogenes. In 6 patients with S. pyogenes septicaemia, fatal endocarditis and spinal osteomyelitis have each occurred once, and 3 patients have had recurrent episodes of septicaemia. The management of septicaemia in these patients must include a search for metastatic infection, and prolonged therapy with 2 antistaphylococcal agents is necessary to ensure eradication of infection. Access site infection in dialysis patients must be treated vigorously, and recognized as potentially hazardous by patients. The risk of sepsis in dialysis and transplant patients cannot be excluded, but devastating consequences may be avoided by simple measures.

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Section: Management Of Infectionmentioning

confidence: 99%

Staphylococcal septicaemia, endocarditis, and osteomyelitis in dialysis and renal transplant patients

Nicholls

Edward

Catto

1980

Postgraduate Medical Journal

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“…Έλα κέζν πνζνζηφ θνξείαο S. aureus 37.2% έρεη βξεζεί ζην γεληθφ πιεζπζκφ (171,172,184,191,192,193,194,195,196). Σα επίπεδα απνηθηζκνχ είλαη πςειφηεξα ζε ρξήζηεο ελδνθιεβίσλ λαξθσηηθψλ (197,198), άηνκα κε ηλζνπιηλν-εμαξηψκελν ζαθραξψδε δηαβήηε (197,198,199,200,201,202), άηνκα πνπ ππνβάιινληαη ζε αηκνθάζαξζε (ΑΚ) ή πεξηηνλατθή θάζαξζε (ΠΚ) (197,203,204,205,206,207,208,209) θαη άηνκα κε ινίκσμε απφ ηνλ ηφ HIV κε ή ρσξίο ηελ παξνπζία πλδξφκνπ Δπίθηεηεο Αλνζνινγηθήο Αλεπάξθεηαο (ΔΑΑ) θαη αλεμάξηεηα απφ ηελ εηζαγσγή ζε λνζνθνκείν (210,211,212,213,214 (6,129,223,224,271,272,273,286,287,291,295,296,297 (4,19,109,115,129,139,221,223,224,226,271,272,273,274,275,276,277,278,279,286,2 99…”

Section: αποθζκδ (Reservoirs)unclassified

“…Ζ ζπζρέηηζε κεηαμχ απνηθηζκνχ κε S. aureus ζε αζζελείο πνπ ππνβάιινληαη ζε ρεηξνπξγηθή επέκβαζε θαη αθφινπζεο ινίκσμεο ρεηξνπξγηθνχ ηξαχκαηνο κε S. aureus ήηαλ ήδε γλσζηή απφ ηα ηέιε ηεο δεθαεηίαο ηνπ 1950(232,233,234). Ο ζρεηηθφο θίλδπλνο γηα ινίκσμε πνηθίιιεη, γηα παξάδεηγκα θπκαίλεηαη απφ 1.8 κέρξη 4.7 γηα θνξείο πνπ ππνβάιινληαη ζε ΑΚ ζε ζρέζε κε κε θνξείο(204,205,208). Ο αληίζηνηρνο ζρεηηθφο θίλδπλνο γηα θνξείο πνπ ππνβάιινληαη ζε ΠΚ κπνξεί λα είλαη αθφκε πςειφηεξνο (εχξνο: 1.8 to 14.0)(235,236,237).…”

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Παράγοντες Κινδύνου Για Νοσοκομειακές Λοιμώξεις Από Ανθεκτικό Στην Μεθικιλλίνη Χρυσίζοντα Σταφυλόκοκκο Σε Σύγκριση Με Λοιμώξεις Από Ευαίσθητο Στη Μεθικιλλίνη Χρυσίζοντα Σταφυλόκοκκο

Μπαραμπούτης¹

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Background. Both total antimicrobial use and specific antimicrobials have been implicated as risk factors for healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) infection. Aims. The aims of the study were: 1.to explore predictors of a new HA-MRSA infection in comparison with a new healthcare-associated methicillin-sensitive Staphylococcus aureus (HA-MSSA), 2. to thoroughly assess the role of recent antibiotic use qualitatively and quantitatively. Methods. The time-period for our study was from October 1997 through September 2001. Applying strict criteria, we identified two groups of inpatients, one with a new HA-MRSA infection and one with a new HA-MSSA infection. We recorded demographic, clinical and antibiotic userelated data up to 30 days before the positive culture date.Results.We identified 127 and 70 patients for each group respectively. Two logistic regression models were carried out to assess the role of antimicrobial use (qualitatively and qualitatively). In model I, duration of hospital stay, presence of chronic wounds, aminoglycoside and fluoroquinolone use retained statistical significance. In model II, duration of hospital stay and history of intubation during the last month stood out as the only significant predictors of a subsequent HA-MRSA infection. No siginificant differences in outcome were noted.Conclusions. The length of exposure to the hospital environment may be the best predictor of a new HA-MRSA infection. Use of aminoglycosides and fluoroquinolones may also stand independently along with presence of chronic ulcers and exposure to surgical procedures. No independent association between quantitative antibiotic use and subsequent HA-MRSA infection was documented.

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Soframycin Treatment of the Nasal Carrier After 14 Years

Stratford

Dixson

1976

Special Problems in Chemotherapy

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The flora of renal haemodialysis shunt sites.

Cited by 15 publications

References 10 publications

Staphylococcal septicaemia, endocarditis, and osteomyelitis in dialysis and renal transplant patients

Staphylococcal septicaemia, endocarditis, and osteomyelitis in dialysis and renal transplant patients

Soframycin Treatment of the Nasal Carrier After 14 Years

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