In centrifugal pumps, the interaction between the rotating impeller and the stationary diffuser generates specific pressure fluctuation patterns. When the pump is operated at off design conditions, these pressure fluctuations increase. The resulting rise of mechanical vibration levels may negatively affect the operational performance and the life span of mechanical components. This paper presents detailed pressure fluctuation measurements performed in a high speed centrifugal pump stage at full scale at various operating conditions. The impeller and stationary part (diffuser, exit chamber) of the pump stage have been equipped with piezo-resistive miniature pressure sensors. The measured data in the impeller have been acquired using a newly developed onboard data acquisition system, designed for rotational speeds up to 6000 rpm. The measurements have been performed synchronously in the rotating and stationary domains. The analysis of pressure fluctuations at the impeller blade trailing edge, which had significantly larger amplitudes as the pressure fluctuations in the stationary domain, allowed the detection and exploration of stalled channels in the vaned diffuser. This stall may be stationary or rotating with different rotational speeds and number of stalled channels, depending on the relative flow rate and the rotational speed of the pump. The stall yields pressure fluctuations at frequencies which are multiples of the rotational speed of the impeller and generates additional sources of mechanical excitation. [6] performed pressure fluctuation measurements in the impeller and different diffusers at varying radial gaps between the impeller and the diffuser. He observed sidebands in the impeller pressure fluctuation spectra generated by a modulation between the vane passing frequency and the rotation frequency due to an uneven circumferential pressure distribution. Guo and Maruta [7] performed pressure fluctuation measurements in a centrifugal pump impeller and they found at high flow rates sidebands in the pressure fluctuation spectra. These sidebands were also a result of a modulation of the vane passing frequency with an uneven circumferential pressure distribution. Eisele et al. [8] used LDV and PTV techniques for a detailed flow analysis in a centrifugal pump diffuser at different operating points of the pump. At part-load flow rate they observed recirculation from the diffuser back into the impeller. Sano et al. [9] used CFD for the numerical simulation of the flow in a diffuser connected to an impeller using a moving grid method. The calculations were made "quasi" 2D, the mesh in the ground view was only one element high. Resulting from the simulation, diffuser rotating stall rotating with 10% of the rotational speed has been found. The simulated flow pattern was in accordance with the measurements of Hergt and Benner [5], Sinha et al. [10] and Wang and Tsukamoto [11]. While in the case studied by Sinha the gap between diffuser and impeller vanes was relatively large (20% of impeller radius), in ...