The food pharmacy: Theory, implementation, and opportunities

Donohue, Juliana A.; Severson, Tracy; Martin, Lauren Park

doi:10.1016/j.ajpc.2020.100145

Cited by 20 publications

(11 citation statements)

References 48 publications

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“…Food and nutrition play critical roles in the management, prevention, treatment, and in some cases, reversal of human diseases ( 1 , 2 ). Accordingly, several advanced analytical methods have been developed to access food's quality and implement the food pharmacy, which in turn may increase consumption of healthful diets ( 3 ). Among them, metabolomics has emerged as the most important tool for chemical characterization of the metabolome underpinning the phenotype of organisms through the qualitative and quantitative analysis of all metabolites and the evaluation of changes in the metabolite profiles due to stresses or perturbations ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

The Dark Pigment in the Sesame (Sesamum indicum L.) Seed Coat: Isolation, Characterization, and Its Potential Precursors

et al. 2022

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Sesame is a worldwide oilseed crop used in the food pharmacy. Its seed phenotypes determine the seed quality values. However, a thorough assessment of seed coat metabolites is lacking, and the dark pigment in the seed coat is not well-characterized. Herein, we report the isolation of melanin by the alkali method from the black and brown sesame seeds. Physicochemical methods, including scanning electron microscopy (SEM), solubility, precipitation, UV-Vis spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, and thermogravimetric-differential scanning calorimetry (TG-DSC), were used to characterize the sesame melanins. The results clearly showed that the isolated pigments were similar to melanin from other sources. Both melanins were heat-stable and exhibited numerous characteristic absorption peaks. Through a comprehensible LC-MS/MS-based metabolome profiles analysis of NaOH and methanol extracts of black and white sesame seeds, caffeic, protocatechuic, indole-carboxylic, homogentisic, ferulic, vanillic, and benzoic acids were identified as the potential precursors of the sesame melanin. Our findings widen our understanding of dark seeds pigmentation in sesame. Furthermore, they show that black sesame seeds are promising sources of edible melanin for food and biotechnological applications.

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Section: Introductionmentioning

confidence: 99%

The Dark Pigment in the Sesame (Sesamum indicum L.) Seed Coat: Isolation, Characterization, and Its Potential Precursors

et al. 2022

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“… 141 Food pharmacies are designed to increase public access to fruits and vegetables and fully integrate the concept of “food is medicine” into health care systems. 142 These centers address financial barriers, knowledge gaps regarding healthy eating, and cooking skills by prescribing fruits and vegetables to patients. Community outreach programs have been successful in dietary changes through education, group counseling, and culinary medicine.…”

Section: Approaches To Nutrition Counseling In CV Healthmentioning

confidence: 99%

A Heart-Healthy Diet for Cardiovascular Disease Prevention: Where Are We Now?

Diab¹,

Dastmalchi²,

Gulati³

et al. 2023

VHRM

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Purpose of Review The relationship between cardiovascular health and diet is evolving. Lifestyle modifications including diet changes are the primary approach in managing cardiometabolic risk factors. Thus, understanding different diets and their impact on cardiovascular health is important in guiding primary and secondary prevention of cardiovascular disease (CVD). Yet, there are many barriers and limitations to adopting a heart healthy diet. Recent Findings Diets rich in fruits, vegetables, legumes, whole grains, and lean protein sources, with minimization/avoidance of processed foods, trans-fats, and sugar sweetened beverages, are recommended by prevention guidelines. The Mediterranean, DASH, and plant-based diets have all proven cardioprotective in varying degrees and are endorsed by professional healthcare societies, while other emerging diets such as the ketogenic diet and intermittent fasting require more long-term study. The effects of diet on the gut microbiome and on cardiovascular health have opened a new path for precision medicine to improve cardiometabolic risk factors. The effects of certain dietary metabolites, such as trimethylamine N-oxide, on cardiometabolic risk factors, along with the changes in the gut microbiome diversity and gene pathways in relation to CVD management, are being explored. Summary In this review, we provide a comprehensive up-to-date overview on established and emerging diets in cardiovascular health. We discuss the effectiveness of various diets and most importantly the approaches to nutritional counseling where traditional and non-traditional approaches are being practiced, helping patients adopt heart healthy diets. We address the limitations to adopting a heart healthy diet regarding food insecurity, poor access, and socioeconomic burden. Lastly, we discuss the need for a multidisciplinary team-based approach, including the role of a nutrition specialist, in implementing culturally-tailored dietary recommendations. Understanding the limitations and finding ways to overcome the barriers in implementing heart-healthy diets will take us miles in the path to CVD prevention and management.

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“…The concept of food pharmacy is a currently emerging sector that is designed to increase the approach and consumption of healthy food options that are more focused on nutritional value. In the past 25 years, the spread of chronic diet-related diseases like obesity, Type 2 diabetes mellitus, hypertension, and other metabolic disorders has increased the mortality rate globally [ 18 , 19 ]. A clinical pharmacist can improve the patient's understanding of nutrition and make the food diet easy to follow, which will render better diet-related health outcomes.…”

Section: Role Of Clinical Pharmacist In Developing Diet Charts For In...mentioning

confidence: 99%

A Glycemic Diet Improves the Understanding of Glycemic Control in Diabetes Patients During Their Follow-Up

Sabarathinam

2023

Future Sci. OA

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The food pharmacy: Theory, implementation, and opportunities

Cited by 20 publications

References 48 publications

The Dark Pigment in the Sesame (Sesamum indicum L.) Seed Coat: Isolation, Characterization, and Its Potential Precursors

The Dark Pigment in the Sesame (Sesamum indicum L.) Seed Coat: Isolation, Characterization, and Its Potential Precursors

A Heart-Healthy Diet for Cardiovascular Disease Prevention: Where Are We Now?

A Glycemic Diet Improves the Understanding of Glycemic Control in Diabetes Patients During Their Follow-Up

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