BACKGROUND: The COVID-19 pandemic has become a major cause of stress and anxiety at work. OBJECTIVE: To examine the effects of the support provided to the employees by the workplaces about the depression, anxiety, stress, job satisfaction of the employees during the COVID-19. METHOD: The inclusion criterias were as follows: being between 18 and 65 years old, working at the time of the survey. The study self-administered included Depression-Anxiety-Stress Scale (DASS), Organizational Support Perception Scale, Job Satisfaction Scale (JSS). RESULTS: In total, 260 people (mean age 38.17±14.9 years, 148 female) completed the survey. Extremely severe depression displayed on 39.9 %, extremely severe anxiety on 37.1%, and severe stress on 28.3% of the participants. Scores for depression (9.6±9.03), anxiety (7.2±7.04), stress (11.7±7.8) were also high for employees. It was observed that the average of organizational support score was 30.4±7.24, and the average job satisfaction score was 28.6±5.35. There was a statistically significant positive correlation between organizational support and job satisfaction (r = 0.562, p = 0.00). Considering the relationship between organizational support and DASS scale; there was negative correlation between (r =-0.161, p = 0.013). The results of the regression indicated that the model explained 32.9 % of the variance and that the model was a significant predictor, F (2,66)=117.145, p < 0.001. CONCLUSION: Organizational support are associated with a decline in mental health and job satisfaction. Health-promotion strategies directed at adopting or maintaining positive job organizational support-related behaviors should be utilized to address increases in psychological distress during the pandemic.