2021
DOI: 10.1101/2021.06.24.449666
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

The Forget-Me-Not dHCP study: 7 Tesla high resolution diffusion imaging in the unfixed post-mortem neonatal brain

Abstract: Diffusion MRI of the neonatal brain allows investigation of the organisational structure of maturing fibres during brain development. Post-mortem imaging has the potential to achieve high resolution by using long scan times, enabling precise assessment of small structures. The Forget-Me-Not study, part of the Developing Human Connectome Project (dHCP), aims to acquire and publicly distribute high-resolution diffusion MRI data for unfixed post-mortem neonatal brain at 7T with a custom-built head coil. This pape… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2021
2021
2022
2022

Publication Types

Select...
1
1

Relationship

2
0

Authors

Journals

citations
Cited by 2 publications
(2 citation statements)
references
References 73 publications
0
2
0
Order By: Relevance
“…Several datasets are under active preparation for future release to the Digital Brain Bank , notably extending the Digital Anatomist and Digital Pathologist categories beyond human tissue for neuroanatomical and neuropathological investigations. These datasets include — Digital Anatomist : (1) Forget-Me-Not developing Human Connectome Project (dHCP) study ( Wu et al, 2021 ), providing diffusion MRI datasets acquired in unfixed, post-mortem neonatal brains; (2) BigMac dataset ( Howard et al, 2019a ) providing in vivo MRI, post-mortem MRI, PLI, and immunohistochemistry in a single, whole macaque brain. Digital Brain Zoo : further primate species are currently in preparation, as are extensions into orders Carnivora and Rodentia.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Several datasets are under active preparation for future release to the Digital Brain Bank , notably extending the Digital Anatomist and Digital Pathologist categories beyond human tissue for neuroanatomical and neuropathological investigations. These datasets include — Digital Anatomist : (1) Forget-Me-Not developing Human Connectome Project (dHCP) study ( Wu et al, 2021 ), providing diffusion MRI datasets acquired in unfixed, post-mortem neonatal brains; (2) BigMac dataset ( Howard et al, 2019a ) providing in vivo MRI, post-mortem MRI, PLI, and immunohistochemistry in a single, whole macaque brain. Digital Brain Zoo : further primate species are currently in preparation, as are extensions into orders Carnivora and Rodentia.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, we present a previously unpublished project providing one of the highest-resolution whole-brain human diffusion MRI datasets ever acquired (500 μm isotropic resolution). The Digital Brain Bank will continue to grow over the coming years, with a number of further datasets already at the early stages of curation ( Howard et al, 2019a ; Martins-Bach et al, 2021 ; Martins-Bach et al, 2020 ; Wu et al, 2021 ).…”
Section: Introductionmentioning
confidence: 99%