Loss of the guide wire is a rare, relatively dangerous, and preventable complication. Inattention is the main cause of the retained guide wires. The diagnosis is simple, but they are usually disregarded by the radiologists. The guide wires should be removed as quickly and completely as possible to prevent any complication. The interventional angiography is usually successful as the first line therapy. as the jugular, subclavian, femoral and brachial veins. Complications associated with the central venous catheters are infection, failure to place the catheter, arterial puncture, improper catheter position, pneumothorax, hematoma, hemothorax, asystolic cardiac arrest of unknown etiology, and inferior vena cava (IVC) trauma (1).