The formation of sulfur trioxide radical anion during the prostaglandin hydroperoxidase-catalyzed oxidation of bisulfite (hydrated sulfur dioxide).

Mottley, Carolyn; Mason, Ronald P.; Chignell, Colin F.; Sivarajah, Kandiah; Eling, Thomas E.

doi:10.1016/s0021-9258(18)34633-7

Cited by 104 publications

(30 citation statements)

References 34 publications

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“…• − has been reported to be generated in the prostaglandin hydroperoxidase-catalyzed oxidation of sulfite and in the horseradish peroxidase-H 2 O 2 oxidation of sulfite. 45,46 It has been reported that the xanthine oxidase/H 2 O 2 system is also capable of generating SO 3…”

Section: Introductionmentioning

confidence: 99%

DNA damage induced by sulfite autoxidation catalyzed by copper(ii) tetraglycine complexes

et al. 2005

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Copper(II)/(III) tetraglycine complexes were investigated for their ability to catalyze the autoxidation of sulfite resulting in oxidative DNA damage. The focus of this work is on DNA damage by Cu(III) and oxysulfur radicals formed by the oxidation of S(IV) oxides by dissolved oxygen in the presence of Cu(II) tetraglycine complexes. The results suggest that sulfite is rapidly oxidized by oxygen in the presence of Cu(II) complexes producing Cu(III) tetraglycine, which can be monitored spectrophotometrically at 365 nm. A synergistic effect of Cu(II) with a second metal ion (Ni(II), Co(II) or Mn(II) traces) was observed.

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Section: Introductionmentioning

confidence: 99%

DNA damage induced by sulfite autoxidation catalyzed by copper(ii) tetraglycine complexes

et al. 2005

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“…While the upregulation of these genes does suggest oxidative stress reactions, such as oxidation of cysteine residues, the mechanism of sulfite radical formation from SO 2 under these conditions is unclear. Nevertheless, some mechanisms for sulfite radical formation have been previously proposed, including autoxidation through catalysis with transition metals such as manganese ( 44 ) and enzymatic oxidation with peroxidases ( 45 ). Furthermore, it is also possible that protein damage occurs through both oxidative damage and nucleophilic substitution.…”

Section: Resultsmentioning

confidence: 99%

Analysis of Transcriptomic Response to SO₂by Oenococcus oeni Growing in Continuous Culture

et al. 2021

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Malolactic fermentation is an indispensable step in the elaboration of most wines and is generally performed by Oenococcus oeni , a Gram-positive heterofermentative lactic acid bacterium species. While O. oeni is tolerant to many of the wine stresses, including low pH and high ethanol concentrations, it has high sensitivity to SO 2 , an antiseptic and antioxidant compound regularly used in winemaking.

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“…Non-enzymatic autooxidation or peroxidase-catalyzed oxidation of sulfite occurs by a one-electron oxidation step. In this case, a sulfur trioxide radical is produced as an intermediate product of sulfite metabolism (Mottley et al, 1982). Previous studies have reported that sulfur and oxygen-centered free radicals may play an important role in sulfite toxicity (Abedinzadeh, 2001;Inouye et al, 1980;Niknahad and O'Brien, 2008;Shi, 1994).…”

Section: Discussionmentioning

confidence: 99%

Hippocampal neuron number loss in rats exposed to ingested sulfite

et al. 2011

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Sulfite, which is continuously formed in the body during metabolism of sulfur-containing amino acids, is commonly used in preservatives. It has been shown that there are toxic effects of sulfite on many cellular components. The aim of this study was to investigate the possible toxic effects of sulfite on pyramidal neurons by counting cell numbers in CA1 and CA2-CA3 subdivisions of the rat hippocampus. For this purpose, male albino rats were divided into a control group and a sulfite group (25 mg/kg). Sulfite was administered to the animals via drinking water for 8 weeks. At the end of the experimental period, brains were removed and neurons were estimated in total and in a known fraction of CA1 and CA2-CA3 subdivisions of the left hippocampus by using the optical fractionator method--a stereological method. Results showed that sulfite treatment caused a significant decrease in the total number of pyramidal neurons in three subdivisions of the hippocampus (CA1 and CA2-CA3) in the sulfite group compared with the control group (p < 0.05, Mann Whitney U test). It was concluded that exogenous administration of sulfite causes loss of pyramidal neurons in CA1 and CA2-CA3 subdivisions of the rat hippocampus.

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The formation of sulfur trioxide radical anion during the prostaglandin hydroperoxidase-catalyzed oxidation of bisulfite (hydrated sulfur dioxide).

Cited by 104 publications

References 34 publications

DNA damage induced by sulfite autoxidation catalyzed by copper(ii) tetraglycine complexes

DNA damage induced by sulfite autoxidation catalyzed by copper(ii) tetraglycine complexes

Analysis of Transcriptomic Response to SO₂by Oenococcus oeni Growing in Continuous Culture

Hippocampal neuron number loss in rats exposed to ingested sulfite

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The formation of sulfur trioxide radical anion during the prostaglandin hydroperoxidase-catalyzed oxidation of bisulfite (hydrated sulfur dioxide).

Cited by 104 publications

References 34 publications

DNA damage induced by sulfite autoxidation catalyzed by copper(ii) tetraglycine complexes

DNA damage induced by sulfite autoxidation catalyzed by copper(ii) tetraglycine complexes

Analysis of Transcriptomic Response to SO2by Oenococcus oeni Growing in Continuous Culture

Hippocampal neuron number loss in rats exposed to ingested sulfite

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Product

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Analysis of Transcriptomic Response to SO₂by Oenococcus oeni Growing in Continuous Culture