The French Experience with a Population-Based Esophageal Atresia Registry (RENATO)

Sfeir, Rony; Aumar, Madeleine; Sharma, Dyuti; Labreuche, Julien; Dauchet, Luc; Gottrand, Frederic

doi:10.1055/a-2206-6837

Cited by 4 publications

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…EA/TEF is a serious congenital malformation of the digestive tract during the neonatal period, with an incidence of 1/2500–1/4500. 1 , 2 , 3 , 4 Type D EA/TEF refers to EA combined with distal and proximal TEFs, and it accounts for less than 1% of all EA types. 5 In recent years, the incidence of type D EA/TEF has been reported to be between 0% and 6.42% in several large cohort studies.…”

Section: Discussionmentioning

confidence: 99%

“…Chest radiography, esophagography, and bronchoscopy are commonly used for diagnosis of EA/TEF. 1 , 3 However, for type D EA/TEF, esophagography cannot reliably detect proximal TEFs, and risks such as aspiration of contrast medium and radiation overdose cannot be excluded. 9 In our study, only one patient (7.1%) was diagnosed with type D EA by esophagography before surgery, which indicated that the diagnostic value of esophagography for type D EA was limited.…”

Section: Discussionmentioning

confidence: 99%

“…Esophageal atresia (EA) and tracheoesophageal fistula (TEF) are rare congenital anomalies that have attracted the attention of pediatric surgeons. 1 , 2 , 3 , 4 Type D EA, the least common type, is characterized by EA with both proximal and distal TEFs and has been reported to occur in less than 1% of EA cases. 5 Only a few articles have reported this rare anomaly.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Diagnose and treatment for Type D congenital esophageal atresia with tracheoesophageal fistula

Wang,

Zhao,

Zhang

et al. 2024

Pediatric Investigation

View full text Add to dashboard Cite

ImportanceType D esophageal atresia (EA) with tracheoesophageal fistula (TEF) is characterized by EA with both proximal and distal TEFs. It is a rare congenital anomaly with a very low incidence.ObjectiveTo investigate diagnostic and treatment strategies for this rare condition.MethodsWe retrospectively reviewed the clinicopathological features of patients with EA/TEF treated at our institution between January 2007 and September 2021.ResultsAmong 386 patients with EA/TEF, 14 (3.6%) had type D EA/TEF. Only two patients were diagnosed with proximal TEF preoperatively. Seven patients were diagnosed intraoperatively. Five patients were missed for diagnosis during the initial surgery but was later confirmed by bronchoscopy. During the neonatal period, seven patients underwent a one‐stage repair of proximal and distal TEF via thoracoscopy or thoracotomy. Due to missed diagnosis and other reasons, the other 7 patients underwent two‐stage surgery for repair of the proximal TEF, including cervical incision and thoracoscopy. Ten of the 14 patients experienced postoperative complications including anastomotic leakage, pneumothorax, esophageal stricture, and recurrence. Patients who underwent one‐stage repair of distal and proximal TEF during the neonatal period showed a higher incidence of anastomotic leak (4/7). In contrast, only one of seven patients with two‐stage repair of the proximal TEF developed an anastomotic leak.InterpretationType D EA/TEF is a rare condition, and proximal TEFs are easily missed. Bronchoscopy may aim to diagnose and determine the correct surgical approach. A cervical approach may be more suitable for repairing the proximal TEF.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Diagnose and treatment for Type D congenital esophageal atresia with tracheoesophageal fistula

Wang,

Zhao,

Zhang

et al. 2024

Pediatric Investigation

View full text Add to dashboard Cite

show abstract

Treatment of Esophageal Atresia in Germany: Analysis of National Hospital Discharge Data From 2016 to 2022

Ungruh,

Hubertus,

Widenmann

et al. 2025

Journal of Pediatric Surgery

View full text Add to dashboard Cite

Prevalence, Mortality, and Associated Anomalies in Esophageal Atresia: A Retrospective Study of Finnish Population Data (2004–2017)

Alikärri,

Helenius,

Heiskanen

et al. 2024

Eur J Pediatr Surg

View full text Add to dashboard Cite

Introduction The aim of the study was to investigate the prevalence of esophageal atresia (EA), frequency of associated anomalies and mortality during 2004–2017 in the Finnish population. We hypothesized the Spitz classification and the presence of other congenital malformations would predict mortality in patients with EA as well as assumed the survival to be high among patients with EA. Material and Methods This retrospective, population-based study was based on the registries maintained by THL Finnish Institute for Health and Welfare and Statistics Finland. The cases were identified and classified according to ICD-9 and ICD-10 codes and accompanying written diagnosis. Associated anomalies were classified based on the EUROCAT criteria, and minor anomalies were excluded. All statistical tests were performed as two-sided significance level set at p<0.05. Chi-square test or Fisher’s exact test were utilized for categorical variables. The change in prevalence rates during the study period was evaluated with linear regression. Results In total, 337 cases with EA were identified including 295 (87.5%) live births, 17 (5.0%) stillbirths and 25 (7.4%) terminations of pregnancy. The total prevalence for EA in Finland was 4.17/10 000 births with no significant change during the study period, P=0.35. Neonatal mortality was 5% (n=15) and 1-year survival 91.5%. Mortality was associated to syndromic cases (p=0.002). The Spitz classification predicted the neonatal mortality better than cardiac anomalies alone (p<0.001 and p=0.6, respectively). Type C was the most common atresia type (65.9%) followed by type A (14.8%) and B (6.8%). The most common group of associated malformations were heart defects (35.0%) followed by other gastrointestinal tract malformations (15.3%) and limb anomalies (12.2%). Syndromic cases (12.2%) were associated with type A and B atresias (p=0.001). VACTERL association was observed in 16.6% of the cases. Conclusion The overall prevalence of EA remains stable and relatively high in Finland. Despite the high prevalence of co-occurring malformations, the overall survival rate is high. Spitz classification predicted neonatal survival well.

show abstract

The French Experience with a Population-Based Esophageal Atresia Registry (RENATO)

Cited by 4 publications

References 20 publications

Diagnose and treatment for Type D congenital esophageal atresia with tracheoesophageal fistula

Diagnose and treatment for Type D congenital esophageal atresia with tracheoesophageal fistula

Treatment of Esophageal Atresia in Germany: Analysis of National Hospital Discharge Data From 2016 to 2022

Prevalence, Mortality, and Associated Anomalies in Esophageal Atresia: A Retrospective Study of Finnish Population Data (2004–2017)

Contact Info

Product

Resources

About