1994
DOI: 10.5144/0256-4947.1994.491
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The Frequency of Glucose-6-Phosphate Dehydrogenase Phenotypes and Sickle Cell Genes in Al-Qatif Oasis

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Cited by 10 publications
(6 citation statements)
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“…The high frequency of G6PD deficiency (11.61 %) in malaria endemic populations of Cameroon corroborates the role malaria play in the distribution of G6PD genes in most malaria endemic areas in the world (El-Hazmi and Warsy, 1994). The percentage gene frequencies for G6PD deficiency of hemizygous males were computed to be 9.21 % and 10.85 % for the NW and SW populations respectively.…”
Section: Discussionsupporting
confidence: 58%
“…The high frequency of G6PD deficiency (11.61 %) in malaria endemic populations of Cameroon corroborates the role malaria play in the distribution of G6PD genes in most malaria endemic areas in the world (El-Hazmi and Warsy, 1994). The percentage gene frequencies for G6PD deficiency of hemizygous males were computed to be 9.21 % and 10.85 % for the NW and SW populations respectively.…”
Section: Discussionsupporting
confidence: 58%
“…The possible protective mechanism of this protection was investigated in the population of Bamenda district of Cameroon which was earlier revealed to have malaria prevalence of 42.2%, most of the plasmodial infection (93.7%) being caused by Plasmodium falciparum (Awah & Uzoegwu, 2007). The 10.4% incidence of G6PD deficiency gene screened for this population during this study is similar to most of the incidences reported for most of the malaria endemic areas of the world (El-Hazmi & Warsy, 1994;Allison, 2004). Our major observation in this study that G6PD nondeficient individuals were more vulnerable to malaria disease and subsequently exhibited more severe malarial anaemia and symptoms, higher parasite density, more frequency of plasmodial attack and lower Hb concentration during plasmodial infection than the enzyme deficient cohorts seem to support the hypothesis that this enzyme deficiency might have arisen in a bid to fight against falciparum malaria (Kar et al, 1990).…”
Section: Discussionsupporting
confidence: 60%
“…The 0.1% incidence rate of SCD and other Hb variant disease in the Lebanese population is higher than the UAE (0.67%) and lower than the Eastern provinces of Saudi Arabia (3.8%) [11], [14], [21], [22]. Compared to other Arab countries such as Libya (0.37%), Yemen (0.9%), and Bahrain (0.6–2.1%), the incidence of the disease in Lebanon is relatively low.…”
Section: Discussionmentioning
confidence: 99%