The frequency of <i>Trichmonas vaginalis, candida albicans</i> and bacterial vaginosis in vaginal smear from women of reproductive age

Al-Harbi, Nuha Y.; Hussein, Raflaa S.H.; Jabuk, Susan I.A.; Jabuk, Sura I.A.

doi:10.5958/0976-5506.2018.00929.4

Cited by 2 publications

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“…Дослідження демонструють можливість різних поєднань поширених причин АВВ (поєднання БВ з наявністю аеробної флори), які раніше вважалися теоретично неможливими з огляду на різні умови (аеробні та анаеробні) існування мікроорганізмів [47][48][49][50][51][52][53]. Проте нещодавні наукові досягнення в розумінні складної структури та функції біоплівок розкривають механізми співіснування різної флори на слизовій піхви в умовах порушення нормального біоценозу [54][55][56][57].…”

Section: причини рецидивного перебігу вагінальних дисбіозів та інфекц...unclassified

Benefits and limitations of clinical assessment of abnormal vaginal discharge etiology

Tutchenko,

Tatarchuk,

Borysova

et al. 2023

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Abnormal vaginal discharge (AVD) is a common syndrome. Its management is addressed in many evidence-based guidelines: International Union of Sexually Transmitted Infections (IUSTI) and WHO Guidelines for management of vaginal discharge (2018); American College of Obstetrics and Gynecology (ACOG) Practice Bulletin No. 215 «Vaginitis in non-pregnant patients» (2020); U.S. Centers for Disease Control and Prevention (CDC) Guidelines for the treatment of sexually transmitted diseases (2021) etc. In December 2022, the Ministry of Health of Ukraine approved an adapted Clinical Guidelines and Standards of Medical Care “Abnormal vaginal discharge”.A special aspect of AVD management is frequent recurrence. Among the many hypotheses of the etiology of the recurrent course of vaginal infections the clinical aspect of difficulties of identifying all pathogens in case of mixed forms deserves special attention. Thus, there is need to presume the possibility of a mixed etiology of AVD or an atypical course of mono-infection at the stage of clinical examination.This review focuses on the role of vaginal discharge pH measuring both in the clinical stage of diagnosing the causes of AVD and in the interpreting laboratory results. Vaginal pH testing is an important component of the clinical stage in diagnostics of the AVD causes. This feasible and quick study allows objectifying the vaginal dysbiosis with a decrease in lactoflora and lactic acid value, which requires further laboratory diagnostics during the examination. Also it is an integral part of the Amsel criteria in the diagnostics of bacterial vaginosis, and vaginal health index to assess the degree of vaginal atrophy in menopause. Vaginal pH testing improves the diagnosis of difficult-to-detect infections and rare causes of AVD. Also, this method is useful for telemedicineto prevent unnecessary medical examinations, laboratory tests and self-treatment, or vice versa, to confirm the need for a specialist consultation.

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Section: причини рецидивного перебігу вагінальних дисбіозів та інфекц...unclassified

Benefits and limitations of clinical assessment of abnormal vaginal discharge etiology

Tutchenko,

Tatarchuk,

Borysova

et al. 2023

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“…Фізіологічний показник [9][10][11]. Слід зазначити, що найчастіше причинами виникнення АВВ, згідно зі світовими рекомендаціями та чинними нормативними документами МОЗ України, стають бактеріальний вагіноз, аеробний вагініт, вульвовагінальний кандидоз та трихомонадна інфекція [12][13][14][15][16][17][18][19]. І для кожної із зазначених нозологій є характерним певне значення рН, що разом зі скаргами та характером АВВ дає можливість вже навіть без лабораторного підтвердження виставити первинний діагноз та призначити лікування [11].…”

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Modern possibilities of correcting violations of the vaginal biotope in pregnant women at risk in wartime conditions

Zhabchenko,

Lihachov,

Lishchenko

et al. 2023

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Research objective: to determine the effectiveness of a complex local preparation with antiseptic action based on octenidine and repair agent dexpanthenol (Prodexyn) in the syndrome of abnormal vaginal discharge (AVD) in pregnant women with obstetric pathology during the gestation and in the sanitation of the birth canal on the eve of childbirth. Materials and methods. 49 pregnant women were examined and divided into 2 groups: group I – 21 women (including 6 pregnant women with the status of internally displaced persons (IDPs)) with AVD in the period of 14–36 weeks of pregnancy; group II – 28 pregnant women (15 of them IDPs) on the eve of childbirth, who needed sanitation of the birth canal in the period of 37-41 weeks. The selection of patients was based on complaints, objective examination in mirrors and determination of vaginal pH. A bacterioscopic and bacteriological study was carried out if the pH deviates from the norm in order to identify pathogens and control the treatment effectiveness. Prodexyn was prescribed to all women in the vaginal suppositories at night for 10 days from the II trimester of pregnancy. Results. Most of women had a complicated obstetric and gynecological history, chronic inflammatory diseases of the pelvic organs, and viral infections. 87.7% of women had obstetric complications during current pregnancy. In the group I the primary average value of vaginal pH was 4.94 ± 0.02, and was the highest in IDPs (5.0-5.3). In the group II the pH before delivery at the initial screening was 5.1 ± 0.03, and in IDPs it was 5.7. Bacterioscopic examination in both groups showed a large number of leukocytes, cocci and fungal flora. Bacteriological examination in both groups showed a total of 11 pathogenic and opportunistic pathogens in various 2–3 component microbial and microbial-fungal associations against the background of a significant decrease in the number of lactobacilli. Single cases of Staphylococcus aureus and Streptococcus agalactiae (in group I) and Streptococcus viridans (in group II) were found. After sanitation the state of the vaginal biotope significantly improved in the majority of pregnant women of both groups. pH in group I was 4.51 ± 0.013, in group II was 4.55 ± 0.03. According to bacterioscopy, the number of leukocytes, coccal, bacillus and fungal flora significantly decreased in both groups. Bacteriological examination showed positive dynamics of the microflora concentration and the amount of its species spectrum. The lactobacilli concentration increased in both groups. Worse indicators of the vaginal biotope restoration were observed in IDPs, especially in the I group in the II–III trimesters, which required an extension of the treatment course for another 5–10 days. Conclusions. The complex local preparation with antiseptic action Prodexyn for AVD in pregnant women with obstetric pathology has shown its effectiveness and safety. As a result of the treatment, the number of pathogenic and conditionally pathogenic flora decreased significantly, with a simultaneous increase in the saprophytic flora and lacISSN 2309-4117tobacilli concentration.

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The frequency of Trichmonas vaginalis, candida albicans and bacterial vaginosis in vaginal smear from women of reproductive age

Cited by 2 publications

References 0 publications

Benefits and limitations of clinical assessment of abnormal vaginal discharge etiology

Benefits and limitations of clinical assessment of abnormal vaginal discharge etiology

Modern possibilities of correcting violations of the vaginal biotope in pregnant women at risk in wartime conditions

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