The Functional Significance of Social Cognition in Schizophrenia: A Review

Couture, Shannon M.; Penn, David L.; Roberts, David L.

doi:10.1093/schbul/sbl029

Cited by 1,131 publications

(907 citation statements)

References 112 publications

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“…Extensive research on this subject has brought some light to aspects such as its neural basis, but most of all focusing on this domain as a potential therapeutic target [117]. In fact, social cognition deficits could be the most significant predictor of functionality in patients with schizophrenia, non-redundantly with neurocognition [6].…”

Section: Discussionmentioning

confidence: 99%

Social Cognition, Negative Symptoms and Psychosocial Functioning in Schizophrenia

Madeira¹,

Caldeira²,

Bajouco³

et al. 2016

IJCNMH

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Although functional recovery could be advocated as an achievable treatment goal, many effective interventions for the treatment of psychotic symptoms, such as antipsychotic drugs, may not improve functioning. The last two decades of cognitive and clinical research on schizophrenia were a turning point for the firm acknowledgment of how relevant social cognitive deficits and negative symptoms could be in predicting psychosocial functioning. The relevance of social cognition dysfunction in schizophrenia patients' daily living is now unabated. In fact, social cognition deficits could be the most significant predictor of functionality in patients with schizophrenia, non-redundantly with neurocognition. Emerging evidence suggests that negative symptoms appear to play an indirect role, mediating the relationship between neurocognition and social cognition with functional outcomes. Further explorations of this mediating role of negative symptoms have revealed that motivational deficits appear to be particularly important in explaining the relationship between both neurocognitive and social cognitive dysfunction and functional outcomes in schizophrenia. In this paper we will address the relative contribution of two key constructs-social cognitive deficits and negative symptoms, namely how intertwined they could be in daily life functioning of patients with schizophrenia.

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Section: Discussionmentioning

confidence: 99%

Social Cognition, Negative Symptoms and Psychosocial Functioning in Schizophrenia

Madeira¹,

Caldeira²,

Bajouco³

et al. 2016

IJCNMH

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“…emotion recognition, theory of mind, empathy) (Couture et al 2006;Fehr & Camerer, 2007). Social decision-making (SDM) encompasses multiple facets including trust, cooperation, fairness, altruism, norm-abiding decision-making, punishment, social learning, and competitive social interactions (Rilling & Sanfey, 2011).…”

Section: Introductionmentioning

confidence: 99%

Altered social and non-social decision-making in recreational and dependent cocaine users

et al. 2013

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Background Maladaptive decision-making is assumed to be a core feature of cocaine addiction. Indeed, numerous studies have reported deficits in non-social decision-making tasks and reward-related impulsivity in dependent cocaine users. However, social decision-making has not been examined in cocaine users yet. Moreover, it is unknown if even recreational and non-dependent cocaine use is linked to decisionmaking deficits. Therefore, we investigated whether recreational and dependent cocaine users exhibit alterations in social and non-social decision-making. Method The performance of healthy controls (n = 68), recreational cocaine users (n = 68) and dependent cocaine users (n = 30) in classical decision-making paradigms (Iowa Gambling Task, Delay Discounting) and in social interaction paradigms (Distribution Game, Dictator Game) was assessed. Results Decisions in the social interaction tasks of both cocaine user groups were more self-serving compared with controls as cocaine users preferred higher monetary payoffs for themselves. In the Iowa Gambling Task, only dependent cocaine users were more likely to choose disadvantageous card decks, reflecting worse decision-making. They were also more likely to choose immediate smaller rewards over larger delayed rewards in the Delay Discounting task. Conclusions Our results imply that both recreational and dependent cocaine users are more concerned with their own monetary gain when interacting with another person. Furthermore, primarily dependent cocaine users are less foresighted and more impulsive regarding immediate reward. Overall, social interaction deficits are already present in recreational users, while non-social decision-making deficits occur predominantly in dependent cocaine users. Thus, social interaction training and cognitive remediation strategies may improve treatment success and quality of life in cocaine dependence.

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“…Although schizophrenia and autism have different symptom presentations, ages of onset, and developmental courses, impaired social functioning is a hallmark characteristic of both disorders (DSM-IV-TR), and these social deficits are related to impairments in social cognition (Couture et al, 2006;Hughes et al, 1997;Klin et al, 2002;Pinkham et al, 2003). Behavioral data suggest both disorders show comparable social cognitive deficits, particularly on tasks requiring higher levels of social cognitive skill (i.e.…”

Section: Introductionmentioning

confidence: 99%

Neural bases for impaired social cognition in schizophrenia and autism spectrum disorders

Pinkham

Hopfinger

Pelphrey

et al. 2008

Schizophrenia Research

341

279

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Schizophrenia and autism both feature significant impairments in social cognition and social functioning, but the specificity and mechanisms of these deficits remain unknown. Recent research suggests that social cognitive deficits in both disorders may arise from dysfunctions in the neural systems that underlie social cognition. We explored the neural activation of discrete brain regions implicated in social cognitive and face processing in schizophrenia subgroups and autism spectrum disorders during complex social judgments of faces. Twelve individuals with autism spectrum disorders (ASD), 12 paranoid individuals with schizophrenia (P-SCZ), 12 non-paranoid individuals with schizophrenia (NP-SCZ), and 12 non-clinical healthy controls participated in this cross sectional study. Neural activation, as indexed by blood oxygenation level dependent (BOLD) contrast, was measured in a priori regions of interest while individuals rated faces for trustworthiness. All groups showed significant activation of a social cognitive network including the amygdala, fusiform face area (FFA), superior temporal sulcus (STS), and ventrolateral prefrontal cortex (VLPFC) while completing a task of complex social cognition (i.e. trustworthiness judgments). ASD and P-SCZ individuals showed significantly reduced neural activation in the right amygdala, FFA, and left VLPFC as compared to controls and in the left VLPFC as compared to NP-SCZ individuals during this task. These findings lend support to models hypothesizing well-defined neural substrates of social cognition and suggest a specific neural mechanism that may underlie social cognitive impairments in both autism and paranoid schizophrenia.

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The Functional Significance of Social Cognition in Schizophrenia: A Review

Cited by 1,131 publications

References 112 publications

Social Cognition, Negative Symptoms and Psychosocial Functioning in Schizophrenia

Social Cognition, Negative Symptoms and Psychosocial Functioning in Schizophrenia

Altered social and non-social decision-making in recreational and dependent cocaine users

Neural bases for impaired social cognition in schizophrenia and autism spectrum disorders

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