The Fungal Endobiome of Medicinal Plants: A Prospective Source of Bioactive Metabolites

Kaul, Sanjana; Gupta, Suruchi; Sharma, Supriya; Dhar, Manoj K.

doi:10.1007/978-981-10-5978-0_7

Cited by 5 publications

(1 citation statement)

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“…The isolation and functional characterization of endophytic fungi from various plant species attract increasing attention and have been subject of a number of studies in recent years (for review, see [20][21][22][23][24][25]). A significant part of this research has been directed towards characterization and utilization of the functional diversity of endophytic fungi from traditional medicinal plants, aiming to obtain novel pharmaceutically active biomolecules [26][27][28]. Although the relatively high sugar and phenolic content of RODW makes it a possible substrate for fungal fermentation, to our knowledge the only work reported in this area until now is our recent study on RODW fermentation by the rhizospheric micromycete strain Trichoderma asperellum SL-45 [29].…”

Section: Introductionmentioning

confidence: 99%

Exploring the capacity of endophytic fungi isolated from medicinal plants for fermentation and phenolics biotransformation of rose oil distillation wastewater

Rusanova

Rusanov

Butterweck

et al. 2019

Biotechnology & Biotechnological Equipment

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A total of 139 endophytic fungal isolates derived from 20 medicinal and aromatic plants were tested for their capacity to ferment rose oil distillation wastewater (RODW). Internal transcribed spacer sequence-based phylogenetic analysis affiliated the collected isolates to seven genera and nine different species, of which Alternaria alternata was the most widely represented. The fungal fermentation of RODW was evaluated through analysis of the sugar and phenolics content and phenolics composition. After cultivation in a small volume of RODW, the performed cluster analysis grouped the isolates in four distinct clusters according to their capacity to ferment RODW sugars and phenolics. Further larger volume shake-flask cultivation of a selected subset of fungi with a pronounced RODW fermentation capacity, outlined three groups of isolates with a distinct pattern and dynamics of sugars and phenolics fermentation. High-performance liquid chromatography analysis of RODW phenolics extracts following the fermentation by the selected fungal isolates showed two main types of changes in phenolics composition: (1) changes in the relative abundance of part of the RODW phenolic compounds, mainly due to utilization of sugar residues from the RODW phenolic glycosides and (2) biosynthesis of new phenolic compounds, most of which are specific to the endophytic fungal isolates used for RODW fermentation. The overall results of the study clearly demonstrate that endophytic fungal isolates represent a rich and untapped source for efficient fermentation of RODW and other agro-industrial phenolics-rich wastewaters and highlight their capacity for directional changes and modification of RODW phenolics composition towards further wastewater phenolics valorization.

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