A year has passed since ACS Nano published its first issue and, as with any milestone, it is a natural time for reflection. Our first year has been filled with extraordinary science from our authors, thoughtful discourse with leaders in the field, and forward-looking perspectives on many of the significant topics in our area. We have seen the true multidisciplinary nature of nanoscience by covering far-reaching areas of research, from developing nanomaterials for RNAi delivery 1,2 to computational analyses of singlemolecule electronics. 3 We have had dialogues with pioneers who originated new branches of nanoscience and with international giants and leaders in our field. 4Ϫ7 We have published commentary about key issues, such as the environmental impacts of nanoscience 8 and the emerging technologies that will augment current lithographic techniques.9,10 With 12 issues in print and so much more to come, we reflect back on the past year, and as always, keep an eye to the future.ACS Nano was launched to provide a forum for high-impact and comprehensive articles, perspectives, and reviews in nanoscience and nanotechnology. One of the most common questions we were asked in the months leading up to our first issue was whether there was a need for another journal in this subject area, and we have been gratified and delighted to see that your answer to that question has been a resounding yes! Each month we receive more high-quality manuscript submissions, corresponding to a steady increase in our peer-reviewed content. Our reviewers play a vital role in the quality of our published papers, and we have been delighted by and grateful for their efforts to ensure our authors are given timely, thoughtful, and insightful reviews. Since launching last August, we have also added to our Editorial Advisory Board, welcoming two new membersOProf. A. Paul Alivisatos and Prof. Flemming Besenbacher. They and the other Board members have been an invaluable source of ideas, support, and wisdom for the journal. We are very thankful to have so many of our esteemed peers working to make ACS Nano a success.Over the past year we have achieved many milestones. Two significant indicators of our success was our selection as one of four finalists for the Association of Learned and Professional Society Publishers Award for Best New Journal (with the winner to be determined this fall) and the indexing of all our journal content by Thomson Reuters (ISI). We have had other intangible successes as well; especially satisfying is the feedback that we receive from you, our community. We have been overwhelmed by the favorable comments from our readers, authors, and reviewers. There are many reasons to celebrate.With these accomplishments in hand, we are excited to build on our first year and have many plans to do even more. The upcoming year will be an important one for nanoscience. At the 237th American Chemical Society National Meeting in March 2009 (in Salt Lake City, Utah), the theme will be "Nanoscience: Challenges for the Future". ACS Nano will b...