The Future of Suprapubic Single-incision Laparoscopic Appendectomy

Alyaqout, Khaled; Alghurair, Abdulaziz; Al-Tarrah, Hussain

doi:10.5005/jp-journals-10033-1248

Cited by 1 publication

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“…One trial by Carter and colleagues showed a significantly higher pain intensity for single-incision laparoscopic appendicectomy with significantly increased opioid consumption but without adequate baseline analgesia 50 . Four systematic reviews and meta-analyses displayed no significant benefit in pain intensity attributed to single-incision laparoscopic appendicectomy compared with conventional three-port laparoscopic appendicectomy 56–59 …”

Section: Resultsmentioning

confidence: 99%

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Perioperative pain management for appendicectomy

Freys,

Bigalke,

Mertes

et al. 2024

European Journal of Anaesthesiology

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BACKGROUND Despite being a commonly performed surgical procedure, pain management for appendicectomy is often neglected because of insufficient evidence on the most effective treatment options. OBJECTIVE To provide evidence-based recommendations by assessing the available literature for optimal pain management after appendicectomy. DESIGN AND DATA SOURCES This systematic review-based guideline was conducted according to the PROSPECT methodology. Relevant randomised controlled trials, systematic reviews and meta-analyses in the English language from January 1999 to October 2022 were retrieved from MEDLINE, Embase and Cochrane Databases using PRISMA search protocols. ELIGIBILITY CRITERIA We included studies on adults and children. If articles reported combined data from different surgeries, they had to include specific information about appendicectomies. Studies needed to measure pain intensity using a visual analogue scale (VAS) or a numerical rating scale (NRS). Studies that did not report the precise appendicectomy technique were excluded. RESULTS Out of 1388 studies, 94 met the inclusion criteria. Based on evidence and consensus, the PROSPECT members agreed that basic analgesics [paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs)] should be administered perioperatively for open and laparoscopic appendicectomies. A laparoscopic approach is preferred because of lower pain scores. Additional recommendations for laparoscopic appendicectomies include a three-port laparoscopic approach and the instillation of intraperitoneal local anaesthetic. For open appendicectomy, a preoperative unilateral transverse abdominis plane (TAP) block is recommended. If not possible, preincisional infiltration with local anaesthetics is an alternative. Opioids should only be used as rescue analgesia. Limited evidence exists for TAP block in laparoscopic appendicectomy, analgesic adjuvants for TAP block, continuous wound infiltration after open appendicectomy and preoperative ketamine and dexamethasone. Recommendations apply to children and adults. CONCLUSION This review identified an optimal analgesic regimen for open and laparoscopic appendicectomy. Further randomised controlled trials should evaluate the use of regional analgesia and wound infiltrations with adequate baseline analgesia, especially during the recommended conventional three-port approach. REGISTRATION The protocol for this study was registered with the PROSPERO database (Registration No. CRD42023387994).

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Section: Resultsmentioning

confidence: 99%

“…50 Four systematic reviews and meta-analyses displayed no significant benefit in pain intensity attributed to single-incision laparoscopic appendicectomy compared with conventional three-port laparoscopic appendicectomy. [56][57][58][59]…”

Section: Adult Patientsmentioning

confidence: 99%