In the current 21st century, more and more attention is being focused on so-called technology transfer. Universities and companies are the main actors in this transfer. Forms of cooperation with the commercial sector, i.e., the two-way flow of information and knowledge, are an important component of the modern university, which fulfils the given vision and goals in each region. Each region, in the Czech Republic we call them regions, has different precious resources, and needs at the same time. These needs are reflected by governmental units, including universities and companies, and together they create supply and demand opportunities in the labour market and try to utilise local resources. This article maps the current official forms of cooperation with the commercial sector at two selected Czech universities -the University of Hradec Kralove and the University of West Bohemia in Pilsen. The article aims to describe these activities, from available official sources, university websites, official social networks, and finally from interviews with staff and students at these universities. Another aim of the article is to compare individual activities and discuss the possibilities of sharing good practices in technology transfer between universities in the two regions of East and West Bohemia.