Improved control over nanowire (NW) geometry and composition offers multiple benefits for design material and devices, including uses in complex nanoelectronic circuits, facilitating their organization on substrates, providing more efficient charge transport over large distances, and greater mechanical strength. Te NWs have many interesting thermoelectric, piezoelectric, conducting, and photoconducting properties and are highly reactive with numerous chemicals, allowing Te NWs to be used as templates for NWs of other compositions. Te NWs are made in this work from CdTe nanoparticles (NPs) by slow oxidation. Te NWs with average lengths of 6.63 ( 1.07 µm and aspect ratios of 50 were initially formed. Unexpectedly, the presence of CdSe NPs results in a drastic increase in the length, aspect ratio, and tortuosity of the Te NWs. We believe that Se 2is being incorporated into the Te seeds as elemental Se, fouling them and reducing the number of viable Te seeds, which allows longer Te NWs to form. Excessive amount of CdTe NPs stops the growth of Te NWs completely making the concentration dependence strongly nonmonotonic. The longest tortuous NWs grown in this fashion have lengths of 15.56 ( 4.16 µm and aspect ratios 103. This work reveals a novel process taking place between growing NW and NPs. These finding indicate advantages of using NPs for reaction control for preparation of NW with high practical relevance.