This study aims to investigate the Chongqing office workers cognition on food safety when eating out, then to provide basic reference about the food safety education for the office workers. A questionnaire survey was conducted among 2637 office workers in eight commercial centers of Chongqing municipal main urban districts by street interview, using self-designed questionnaire of Chongqing main urban office workers cognition on food safety when eating out. 2400 valid questionnaires were analyzed. 64.41%(1540/2391) of the office workers would pay attention to food safety problem. 14.73% (352/2390) of the office workers were aware of food safety grade rating, and the awareness rates of male are significant higher than female. When meeting with food safety problems, 80.87% (1936/2394) of the office workers would choose to exchange the dishes, 30.95% (741/2394) of them would remind friends not to consume, 23.73% (568/2394) of them would refuse to pay for the dishes, 10.74% (257/2394) of the office workers would claim for compensation, 9.36% (224/2394) of them would report it to the department concerned, 9.19% (220/2394) of them thought they had bad luck,2.92% (70/2394) of the office workers would choose to disclose it by media. The main channels of food safety information were TV (85.54%, 2087/2385), newspapers (68.60%, 1636/2385), network (55.89%, 1333/2385), and magazines (24.70%, 589/2385). The attention that office workers paid to food safety and the relevant laws, regulations and measures is low, and the office workers lack of right-protection awareness, Besides TV and newspapers, network has become the main sources of information on food safety.