The GHEP–EMPOP collaboration on mtDNA population data—A new resource for forensic casework

Prieto, Lourdes; Zimmermann, Bettina; Goios, Ana; Rodrı́guez-Monge, A; Paneto, Greiciane Gaburro; Alves, Cı́ntia; Alonso, Antonio; Fridman, Cíntia; Cardoso, Sergio; Lima, Gabriela Narcizo de; Anjos, M.J.; Whittle, M.R.; Montesino, M.; Cicarelli, Regina Maria Barretto; Rocha, Ana Mafalda; Albarrán, Cristina; Pancorbo, Marian M. de; Pinheiro, M.F.; Carvalho, M.; Sumita, Denilce R.; Parson, Walther

doi:10.1016/j.fsigen.2010.10.013

Cited by 42 publications

(23 citation statements)

References 16 publications

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“…Twenty-four of these were detected in our modern mtDNA database (5191 Europeans). Nine matches were identified in two larger worldwide databases [31,32]. Only one A4b).…”

Section: Resultsmentioning

confidence: 99%

Mitochondrial DNA variation in the Viking age population of Norway

Krzewińska

Bjørnstad

Skoglund

et al. 2015

Phil. Trans. R. Soc. B

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The medieval Norsemen or Vikings had an important biological and cultural impact on many parts of Europe through raids, colonization and trade, from about AD 793 to 1066. To help understand the genetic affinities of the ancient Norsemen, and their genetic contribution to the gene pool of other Europeans, we analysed DNA markers in Late Iron Age skeletal remains from Norway. DNA was extracted from 80 individuals, and mitochondrial DNA polymorphisms were detected by next-generation sequencing. The sequences of 45 ancient Norwegians were verified as genuine through the identification of damage patterns characteristic of ancient DNA. The ancient Norwegians were genetically similar to previously analysed ancient Icelanders, and to present-day Shetland and Orkney Islanders, Norwegians, Swedes, Scots, English, German and French. The Viking Age population had higher frequencies of K*, U*, V* and I* haplogroups than their modern counterparts, but a lower proportion of T* and H* haplogroups. Three individuals carried haplotypes that are rare in Norway today (U5b1b1, Hg A* and an uncommon variant of H*). Our combined analyses indicate that Norse women were important agents in the overseas expansion and settlement of the Vikings, and that women from the Orkneys and Western Isles contributed to the colonization of Iceland.

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“…Twenty-four of these were detected in our modern mtDNA database (5191 Europeans). Nine matches were identified in two larger worldwide databases [31,32]. Only one A4b).…”

Section: Resultsmentioning

confidence: 99%

Mitochondrial DNA variation in the Viking age population of Norway

Krzewińska

Bjørnstad

Skoglund

et al. 2015

Phil. Trans. R. Soc. B

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“…To better evaluate the geographical distribution of the novel haplogroups, we surveyed published and unpublished CR data from a wide range of populations (Ginther et al 1993;Horai et al 1993;Alves-Silva et al 2000;Moraga et al 2000;Lalueza-Fox et al 2001;García-Bour et al 2004;Tajima et al 2004;Cabana et al 2006;Á lvarez-Iglesias et al 2007;Tamm et al 2007;Carvalho et al 2008;Salas et al 2008;Bobillo et al 2010;Catelli et al 2011;Gayà-Vidal et al 2011;Prieto et al 2011;Sans et al 2011;MC Bobillo, unpubl.). This allowed the identification of 103 putative D1g and D1j mtDNAs (Supplemental Table S3).…”

Section: Phylogeographic Patterns Of D1g and D1jmentioning

confidence: 99%

Rapid coastal spread of First Americans: Novel insights from South America's Southern Cone mitochondrial genomes

Bodner¹,

Perego²,

Huber³

et al. 2012

Genome Res.

171

169

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It is now widely agreed that the Native American founders originated from a Beringian source population ∼15–18 thousand years ago (kya) and rapidly populated all of the New World, probably mainly following the Pacific coastal route. However, details about the migration into the Americas and the routes pursued on the continent still remain unresolved, despite numerous genetic, archaeological, and linguistic investigations. To examine the pioneering peopling phase of the South American continent, we screened literature and mtDNA databases and identified two novel mitochondrial DNA (mtDNA) clades, here named D1g and D1j, within the pan-American haplogroup D1. They both show overall rare occurrences but local high frequencies, and are essentially restricted to populations from the Southern Cone of South America (Chile and Argentina). We selected and completely sequenced 43 D1g and D1j mtDNA genomes applying highest quality standards. Molecular and phylogeographic analyses revealed extensive variation within each of the two clades and possibly distinct dispersal patterns. Their age estimates agree with the dating of the earliest archaeological sites in South America and indicate that the Paleo-Indian spread along the entire longitude of the American double continent might have taken even <2000 yr. This study confirms that major sampling and sequencing efforts are mandatory for uncovering all of the most basal variation in the Native American mtDNA haplogroups and for clarification of Paleo-Indian migrations, by targeting, if possible, both the general mixed population of national states and autochthonous Native American groups, especially in South America.

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“…Hypervariable region I (HVR-I) was analyzed by sequencing DNA randomly for a small percentage (5%) as quality control. These samples were analyzed using primers based on Prieto et al (2011) (see Table 2). …”

Section: Mtdna Analysismentioning

confidence: 99%

Mitochondrial DNA analysis suggests a Chibchan migration into Colombia

et al. 2015

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The characterization of mitochondrial DNA (mtDNA) allows the establishment of genetic structures and phylogenetic relationships in human populations, tracing lineages far back in time. We analysed samples of mtDNA from twenty (20) Native American populations (700 individuals) dispersed throughout Colombian territory. Samples were collected during 1989-1993 in the context of the program Expedición Humana ("Human Expedition") and stored in the Biological Repository of the Institute of Human Genetics (IGH) at the Pontificia Universidad Javeriana (Bogotá, Colombia). Haplogroups were determined by analysis of RFLPs. Most frequent was haplogroup A, with 338 individuals (48.3%). Haplogroup A is also one of the most frequent haplogroups in Mesoamerica, and we interpret our finding as supporting models that propose Chibchan-speaking groups migrated to northern Colombia from Mesoamerica in prehistoric times. Haplogroup C was found in 199 individuals (28.4%), while less frequent were B and D, with 113 and 41 (16% and 6%) individuals, respectively. The haplogroups of nine (9) individuals (1.3%) could not be determined due to the low quality of the samples of DNA. Although all the sampled populations had genetic structures that fit broadly into the patterns that might be expected for contemporary Central and South American indigenous groups, it was found that haplogroups A and B were more frequent in northern Colombia, while haplogroups C and D were more frequent in southern and south-western Colombia.

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The GHEP–EMPOP collaboration on mtDNA population data—A new resource for forensic casework

Cited by 42 publications

References 16 publications

Mitochondrial DNA variation in the Viking age population of Norway

Mitochondrial DNA variation in the Viking age population of Norway

Rapid coastal spread of First Americans: Novel insights from South America's Southern Cone mitochondrial genomes

Mitochondrial DNA analysis suggests a Chibchan migration into Colombia

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