The Global Burden of Childhood Diarrhea

Boschi-Pinto, Cynthia; Lanata, Claudio F.; Black, Robert E.

doi:10.1007/b106524_13

Cited by 40 publications

(31 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This overall incidence has remained relatively stable over the past two decades. [2,15] Most cases occurs in poor and developing areas, mainly Africa and South Asia, where bouts of diarrhoea are more likely to result in death or other severe outcomes. The incidence of diarrheal diseases varies greatly with the seasons and a child's age.…”

Section: Discussionmentioning

confidence: 99%

“…Such disease has been considered a public health concern because of the related costs of second and third level health care and the suffering of children. [1,2] Multifaceted risk factors for diarrhea, such as the nutritional, environmental, socioeconomic, and cultural aspects that are found in these areas, provide settings favorable for the occurrence of the disease. [3] Diarrhea is defined as the passing of at least three loose or watery stools or one bloody loose stool within the last 24 hours.…”

Section: Introductionmentioning

confidence: 99%

“…[7] Studies evaluating the prevalence of childhood diarrhea frequently analyze samples from children under five years of age. [10][11][12] However, children under two are more vulnerable to gastrointestinal infections, [2,[13][14][15] because they have a maturing immune system and because of specific conditions related to physical growth and neuropsychomotor development that result in a physiological vulnerability to illness. [16,17] Therefore, early childhood is the most opportune time to intervene and prevent long-term consequences of poor health outcomes, such as diarrhea and hospitalization.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence and hospitalization rates due to diarrhoea in infants: the 2006 Brazilian National Demographic Health Survey

Konstantyner

Konstanty

Mais

et al. 2015

JER

View full text Add to dashboard Cite

Aim: The aim of this study was to estimate the prevalence of and hospitalization rate due to diarrhea and to identify factors associated with diarrheal disease and related hospitalizations in children less than two years old in Brazil. Methods: This was a cross-sectional study of 1,902 children who were participants in the 2006 National Demographic and Health Survey (Pesquisa Nacional de Demografia e Saúde da Criança e da Mulher -PNDS 2006). To collect data, children's mothers were interviewed. The prevalence of and hospitalization rate due to diarrhea were calculated for the two weeks before the interview and for the last year, respectively. Logistic regression models were fitted to identify the prevalence of diarrhea and the risk factors associated with diarrhea occurrence and related hospitalizations. A complex sample statistical technique was applied for all analyses. Results: The prevalence of diarrhea and hospitalization rate due to diarrhea were 11.9% and 2.6%, respectively. Children living in the North and Northeast regions had a greater risk of diarrhea, while children under 12 months old, those who were receiving age-appropriate exclusive breastfeeding and those with mothers greater than 35 years old were protected against the disease. Male children living in households that did not have a land-floor in the North and Northeast regions had a higher risk of hospitalization due to diarrhea, while children of mothers who had a higher education level (> 4 years) were protected against it. Conclusion: Diarrhea is still a public health problem for children under two years old in Brazil, especially in the North and Northeast regions. Diarrhea control and prevention programs should inform young mothers with lower education levels about children's healthcare, including the benefits of breastfeeding.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence and hospitalization rates due to diarrhoea in infants: the 2006 Brazilian National Demographic Health Survey

Konstantyner

Konstanty

Mais

et al. 2015

JER

View full text Add to dashboard Cite

show abstract

“…La diarrea es una enfermedad frecuente en infantes y niños, donde se presenta como una de las principales causas de malnutrición y elevados niveles de morbilidad y mortalidad, esto último principalmente en regiones del África y el sur de Asia (25) . En Latinoamérica todavía se presenta como una de las principales enfermedades que puede ocasionar hasta 100 muertes en niños al día (ver comunicado del BID 2009).…”

Section: Discussionunclassified

Depleción del suministro de sangre y costo por donaciones indeterminadas del Hospital Nacional Guillermo Almenara Irigoyen

et al. 2017

View full text Add to dashboard Cite

RESUMENObjetivo: Determinar el tipo y frecuencia de enteropatógenos predominantes en diarreas agudas y sus características asociadas en niños atendidos en el Hospital Regional Lambayeque (HRL) -Perú. Materiales y métodos: Se realizó un estudio analítico transversal entre marzo y mayo del 2015 en 70 muestras fecales. Las muestras se estudiaron mediante coprocultivo e inmunocromatografía para la detección de bacterias y virus enteropatógenos respectivamente. Mientras que los enteroparásitos se buscaron mediante examen microscópico directo, tinción de Kinyoun y ELISA para coproantígenos (Entamoeba histolytica, Giardia lamblia y Cryptosporidium spp.). Asimismo se realizó conteo de leucocitos y pruebas químicas (Benedict, Thevenon y Sudan III) para el estudio funcional de la enfermedad diarreica. Resultados: En el 48,6% de muestras se detectó la etiología infecciosa de la diarrea, siendo predominante la causa parasitaria (25,8%), seguida de la bacteriana (17,1%) y viral (5,8%). Los enteropatógenos más frecuentes fueron G. lamblia (18,6%) y Salmonella Enteritidis (10,0%). Se observó asociación entre la cantidad de leucocitos mayor a 100 con la etiología bacteriana (p=0,027), mientras que un número menor de 10 por campo (p=0,002) y el Sudan III positivo (p=0,003) con la etiología parasitaria. Conclusiones: En más de la mitad de muestras (51,4%) no se demostró etiología infecciosa de la diarrea, mientras que Giardia lamblia fue la más frecuente causa de diarrea en la población estudiada. No obstante, es necesaria la implementación de técnicas más sensibles y específicas para la detección de un rango mayor de enteropatógenos con el que se mejore el diagnóstico y tratamiento de la enfermedad.Palabras clave: Diarrea infantil; diarrea infecciosa; giardia lamblia; salmonella enteritidis.Predominant enteropathogens in acute diarrhea and associated variables in children at the Lambayeque Regional Hospital, Peru ABSTRACT Objective: To determine the type and frequency of predominant enteropathogens in acute diarrhea and their associated characteristics in children treated at Hospital Regional Lambayeque (HRL) -Peru. Materials and methods: A cross-sectional analytical study was carried out in 70 fecal samples between March and May 2015. These samples were studied by coproculture and immunochromatography for the detection of enteropathogenic bacteria and viruses, respectively, while enteroparasites were sought by direct microscopic examination, Kinyoun staining method and ELISA for the detection of coproantigens (Entamoeba histolytica, Giardia lamblia and Cryptosporidium spp). Leukocyte count and chemical tests (Benedict, Thevenon and Sudan III) were also performed for the functional study of the diarrheal disease. Results: In 48.6% of the samples, the infectious etiology of diarrhea was detected, prevailing the parasitic cause (25.8%), followed by the bacterial (17.1%) and viral (5.8%) ones. The most common enteropathogens were G. lamblia (18.6%) and Salmonella enteritidis (10.0%). An association between greater than 100 fecal le...

show abstract

“…An estimated 2.5 billion cases of diarrhea occur annually in children under five years of age [2], with an estimated frequency of 2-3 episodes per child per year in developing countries [3]. Diarrheal disease is the second leading cause of mortality in this age group worldwide, after pneumonia.…”

Section: Global Burdenmentioning

confidence: 99%