The Global Burden of Chronic Diseases

Apolipoprotein E genotypes and their relation to lipid levels in a rural South African population 1

“…In sub-Saharan countries where the apoe4 allele is most frequent, the prevalence of cardiovascular disease is low but increasing [28]. In the South African black population, socioeconomic conditions are changing rapidly and are accompanied by dramatic lifestyle and dietary adjustment.…”

‘A chronic disease is a disease which keeps coming back … it is like the flu’: chronic disease risk perception and explanatory models among French- and Swahili-speaking African migrants

“…Non-communicable chronic diseases are now the greatest cause of death in the world (Yach et al 2004). This global epidemiological transition has been linked with adoption of less healthy diets, physical inactivity, tobacco use, urbanisation, increased life expectancy and poverty (World Health Organisation 2005).…”

Differential use of available genetic tests among primary care physicians in the United States: results of a national survey

“…10 -13 It is precisely through advances in the treatment and prevention of highly prevalent conditions that genomics has the greatest potential to improve population health and reduce health disparitiesbut only if PCPs are prepared to incorporate genomic medicine into practice and if such interventions reach those most in need. 14,15 PCPs face several challenges in utilizing genetic tests to enhance clinical care. Most have little experience or training relevant to genetic testing, and many lack confidence and skill in this area of practice.…”