The Global Burden of Ischemic Heart Disease in 1990 and 2010

Moran, Andrew E.; Forouzanfar, Mohammad H.; Roth, Gregory A.; Mensah, George A.; Ezzati, Majid; Flaxman, Abraham D.; Murray, Christopher J L; Naghavi, Mohsen

doi:10.1161/circulationaha.113.004046

Cited by 559 publications

(314 citation statements)

References 27 publications

(31 reference statements)

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“…The Global Burden of Disease 2010 Study described regional differences in the time trends in the incidence of ischemic heart disease for 21 regions in the world 4 .…”

Section: Risk Factor Modification and Altered Incidence Of Acute Cardmentioning

confidence: 99%

Temporal shifts in clinical presentation and underlying mechanisms of atherosclerotic disease

2016

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The concept of "the vulnerable plaque" originated from pathological observations in patients who succumbed to fatal acute coronary syndromes. This recognition spawned a generation of research that led to achievement of considerable understanding of how complicated atherosclerotic plaques form and precipitate thrombotic events.In current practice, an increasing number of patients present with non ST-elevation myocardial infarction (NSTEMI) rather than myocardial infarction (MI) with ST-elevation Key points• An increasing number of patients presenting with myocardial infarction (MI) are diagnosed with a non ST-elevated myocardial infarction (NSTEMI) rather than a MI with ST-elevation (STEMI) and consequently survive their first event.• The shift in the clinical presentations of the acute coronary syndromes mandates a critical reassessment of the underlying mechanisms and the concept of the 3 vulnerable plaque.• The change in clinical presentation and warrant critical re-assessment of currently applied cardiovascular risk scores, pre-clinical experiments, and the usefulness of population data and samples harvested before the application of current preventive interventions.4

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“…The Global Burden of Disease 2010 Study described regional differences in the time trends in the incidence of ischemic heart disease for 21 regions in the world 4 .…”

Section: Risk Factor Modification and Altered Incidence Of Acute Cardmentioning

confidence: 99%

Temporal shifts in clinical presentation and underlying mechanisms of atherosclerotic disease

2016

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“…The global prevalence of congestive heart failure (CHF), especially that of ischaemic aetiology, has increased since 1990 despite the fact that acute myocardial infarction incidence has decreased 1. A total of 26 million people live with CHF worldwide, causing a significant strain on healthcare systems and national health expenditures 2, 3.…”

Section: Introductionmentioning

confidence: 99%

“…The calculation for DALY uses disability weight (DW) as a proportional reduction of normal health on a scale of 0–100% disability 1, 13. Some reports have suggested DW ranges to be 0.037, 0.070, and 0.186 for mild, moderate, and severe CHF, respectively,13, 14, 15 whereas Murray et al .…”

Section: Introductionmentioning

confidence: 99%

Gender‐adjusted and age‐adjusted economic inpatient burden of congestive heart failure: cost and disability‐adjusted life‐year analysis

Salem

Elkhateeb

2017

ESC Heart Failure

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AimsThe two components of disability‐adjusted life year (DALY), years of life lost (YLL) and years lived with disability (YLD), are underutilized in evaluating heart failure with reduced ejection fraction (HFrEF) and in assessing the global burden of disease. We aim to describe both the direct (medical) and the indirect (morbidity and mortality) inpatient cost of congestive heart failure in a high‐income non‐Organization for Economic Cooperation and Development Middle Eastern country in relation to YLL and YLD.Methods and resultsWe used the World Health Organization's global burden of disease methodology to calculate DALY, YLL, and YLD in 174 consecutive prospectively enrolled New York Heart Association Classes II–IV patients in a single‐centre heart failure registry using a 0.4 disability weight and a 3% future age discount. We reported the cost of hospitalization, re‐hospitalization, and non‐invasive and invasive procedures per 1000 HFrEF patients in US dollars (USD). Expressing results as per 1000 HFrEF capita revealed a DALY of 1480 ± 1909 vs. 2177 ± 2547 in women and men, respectively. The costs per HFrEF capita in USD were $909.00 ± 676.1 for a single‐day hospital stay, $7999 per single hospitalization, $12 311 ± 13 840 for annual hospitalizations, $20 486 ± 22 068 for all‐cause hospitalizations, and $37 355 ± 49 336 from the time of diagnosis until death or recovery.ConclusionsIn this study, HFrEF imposed a substantial economic and disability burden on one non‐Organization for Economic Cooperation and Development Middle Eastern country. However, men represented a higher economic burden than women.

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“…Ischemic heart disease (IHD), also known as coronary heart disease, is a leading cause of disease burden worldwide in terms of both years of life lost from IHD deaths and years of disability lived with nonfatal IHD 1. Despite a decrease in age‐standardized mortality of fatal and nonfatal IHD in high‐income countries since 1990, IHD remained as a leading cause of death between 1990 and 2013 in China 2.…”

Section: Introductionmentioning

confidence: 99%

Self‐Rated Health Status and Risk of Ischemic Heart Disease in the China Kadoorie Biobank Study: A Population‐Based Cohort Study

Dong

Pan

Yu³

et al. 2017

JAHA

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BackgroundSelf‐rated health (SRH) is a strong predictor of mortality in different populations. However, the associations between SRH measures and risk of ischemic heart disease (IHD) have not been extensively explored, especially in a Chinese population.Methods and ResultsMore than 500 000 adults from 10 cities in China were followed from baseline (2004–2008) through December 31, 2013. Global and age‐comparative SRH were reported from baseline questionnaires. Incident IHD cases were identified through links to well‐established disease registry systems and the national health insurance system. During 3 423 542 person‐years of follow‐up, we identified 24 705 incident cases of IHD. In multivariable‐adjusted models, both global and age‐comparative SRH was significantly associated with incident IHD. Compared with excellent SRH, the hazard ratios for good, fair, and poor SRH were 1.02 (95% confidence interval [CI], 0.98–1.07), 1.32 (95% CI, 1.27–1.37), and 1.76 (95% CI, 1.68–1.85), respectively. Compared with better age‐comparative SRH, the hazard ratios for same and worse age‐comparative SRH were 1.23 (95% CI, 1.19–1.27) and 1.78 (95% CI, 1.70–1.86), respectively. The associations persisted in all subgroup analyses, although they were slightly modified by study location, education, and income levels.ConclusionsA simple questionnaire for self‐assessment of health status was significantly associated with incident IHD in Chinese adults. Individuals and healthcare providers can use SRH measures as a convenient tool for assessing future IHD risk.

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The Global Burden of Ischemic Heart Disease in 1990 and 2010

Cited by 559 publications

References 27 publications

Temporal shifts in clinical presentation and underlying mechanisms of atherosclerotic disease

Temporal shifts in clinical presentation and underlying mechanisms of atherosclerotic disease

Gender‐adjusted and age‐adjusted economic inpatient burden of congestive heart failure: cost and disability‐adjusted life‐year analysis

Self‐Rated Health Status and Risk of Ischemic Heart Disease in the China Kadoorie Biobank Study: A Population‐Based Cohort Study

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