Given the current circumstances, the phenomenon of regionalism is not surprising because it is evolving at a rapid pace on a global scale. Regionalism as a process continues to expand and take on multiple roles that ultimately shape global trade cooperation, geopolitics, and diplomacy among states. Today, a large number of regional international organizations perform specific institutional functions based on specific preferences and the internal logic of functioning of the member states. The Economic Community of West African States (ECOWAS) is an example of a regional organization on the African continent. Like most intergovernmental or interstate organizations, the ECOWAS is a political union among West African states, originally created by the Lagos Agreement in 1975 to promote economic cooperation and integration among the member states. With the development of international relations on African soil, there was a demand for an accelerated revision of the founding treaties of ECOWAS. In 1993, the mandate of this regional organization was expanded, so the organization generally expanded its scope of action to include the preservation of regional peace and security. However, its effectiveness and efficiency in this domain have been subject to serious criticism. On the other hand, efficiency and effectiveness in terms of regional integration were apparently somewhat more successful. This issue is given special attention in this paper, which points to specific challenges and risks associated with this process, as well as with the implementation of the ECOWAS Agreement. In addition, the analysis is focused on general issues related to the ways and effects of the functioning of regional organizations at the global level.