The global, regional, and national patterns of change in the burden of congenital birth defects, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2040

Bai, Zihao; Han, Jingru; An, Jia; Wang, Hao; Du, Xueying; Yang, Zhaocong; Mo, Xuming

doi:10.1016/j.eclinm.2024.102873

eClinicalMedicine

2024

DOI: 10.1016/j.eclinm.2024.102873

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The global, regional, and national patterns of change in the burden of congenital birth defects, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2040

Zihao Bai,

Jingru Han,

Jia An

et al.

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Cited by 3 publications

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Global assessment of leukemia care quality: insights from the quality of care index (QCI) from 1990 to 2021

Pan,

Liu,

Zhang

et al. 2025

eClinicalMedicine

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Global assessment of leukemia care quality: insights from the quality of care index (QCI) from 1990 to 2021

Pan,

Liu,

Zhang

et al. 2025

eClinicalMedicine

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The burden and trends of heart failure caused by ischaemic heart disease at the global, regional, and national levels from 1990 to 2021

Zhang,

Zheng,

Huang

et al. 2024

European Heart Journal - Quality of Care and Clinical Outcomes

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Background Ischemic heart disease (IHD) is a major cause of heart failure (HF), a condition expected to increasingly affect global health and economics. This study evaluates the global burden, trends, and disparities of HF linked to IHD, aiming to inform health policy development. Methods Data from the Global Burden of Disease Study 2021 (GBD2021) is analyzed using Joinpoint regression, decomposition analysis, and Bayesian age-period-cohort analysis (BAPC). Health disparities are assessed through the Socio-demographic Index (SDI) via the Slope Index of Inequality (SII) and the Concentration Index (CI), with future trends projected from 2022 to 2045. Results In 2021, global HF cases due to IHD were over 19.16 million, with an age-standardized prevalence rate (ASPR) of 228.31 per 100 000 [95% UI, 188.18 to 279.55] and age-standardized years lived with disability (ASYLDs) rate of 20.43 per 100 000 [95% UI, 13.55 to 28.7].In 2021, there was a 2.87% increase in ASPR and ASYLDs compared to 1990, primarily driven by population growth and aging.Significant reductions in global ASPR and ASYLDs disparities are observed, though the disease burden has intensified in countries with lower SDI levels. Projections indicate that by 2045, while the prevalence and YLDs for HF caused by IHD will increase, while the ASPR and ASYLDs are expected to decrease. Conclusion The global burden of HF from IHD remains a significant concern. Urgent improvements in the allocation of medical resources and the implementation of effective prevention and management strategies are necessary to address this issue.

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Epidemiology of Congenital Heart Defects in Perinatal Infants in Guangxi, China

Peng,

Wei,

Huang

et al. 2024

IJGM

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The global, regional, and national patterns of change in the burden of congenital birth defects, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2040

Cited by 3 publications

References 37 publications

Global assessment of leukemia care quality: insights from the quality of care index (QCI) from 1990 to 2021

Global assessment of leukemia care quality: insights from the quality of care index (QCI) from 1990 to 2021

The burden and trends of heart failure caused by ischaemic heart disease at the global, regional, and national levels from 1990 to 2021

Epidemiology of Congenital Heart Defects in Perinatal Infants in Guangxi, China

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