The global survival rate among adult out-of-hospital cardiac arrest patients who received cardiopulmonary resuscitation: a systematic review and meta-analysis

Abstract

Background: To quantitatively summarize the available epidemiological evidence on the survival rate of out-ofhospital cardiac arrest (OHCA) patients who received cardiopulmonary resuscitation (CPR). Methods: We systematically searched the PubMed, Embase, and Web of Science databases, and the references of retrieved articles were manually reviewed to identify studies reporting the outcome of OHCA patients who received CPR. The overall incidence and outcome of OHCA were assessed using a random-effects meta-analysis. Results: A total of 141 eligible studies were included in this meta-analysis. The pooled incidence of return of spontaneous circulation (ROSC) was 29.7% (95% CI 27.6-31.7%), the rate of survival to hospital admission was 22.0% (95% CI 20.7-23.4%), the rate of survival to hospital discharge was 8.8% (95% CI 8.2-9.4%), the pooled 1-month survival rate was 10.7% (95% CI 9.1-13.3%), and the 1-year survival rate was 7.7% (95% CI 5.8-9.5%). Subgroup analysis showed that survival to hospital discharge was more likely among OHCA patients whose cardiac arrest was witnessed by a bystander or emergency medical services (EMS) (10.5%; 95% CI 9.2-11.7%), who received bystander CPR (11.3%, 95% CI 9.3-13.2%), and who were living in Europe and North America (Europe 11.7%; 95% CI 10.5-13.0%; North America: 7.7%; 95% CI 6.9-8.6%).

Study of pre-hospital care of Out of Hospital Cardiac Arrest victims and their outcome in a tertiary care hospital in India

“…6 A systematic review & meta-analysis by Yan et al showed that prehospital stage was the most impactful stage for care of OHCA patients and where efficient CPR from EMS translated to highest incidence of ROSC (36.3%; 95% CI 23.8 -48.9%). 7 This emphasizes the need to educate the community regarding the importance of using an ambulance and EMS systems, so that earlier AED use and ACLS interventions can be administered. 8 Continuing with the quality of the EMS services available to our patient group only 7.8% received CPR, with only 12.5% of ambulances having Basic Life Support (BLS) trained personnel.…”

Finding the right pace: Addressing the transition from manual to mechanical compression devices for out‐of‐hospital cardiac arrest

“…The 1-year global survival rates are ≈7.7% and increase to 12.6% among patients receiving bystander cardiopulmonary resuscitation (CPR). 1 Early initiation of effective compressions with minimal interruptions is essential to maximizing favorable outcomes after out-of-hospital cardiac arrest. In addition, the use of mechanical CPR in resource-limited efforts with prolonged transportation time should still be promoted as a means to support emergency medical services out-of-hospital care.…”

Examining the Prognostic Utility of Frailty for Post-arrest Outcomes Following the Provision of Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis Protocol

“…Despite these efforts, the one-year survival rate is 13% for individuals who experience IHCA and 7% for OHCA. 5,6 Furthermore, the majority of survivors report physical disabilities, cognitive impairment or mental illness, potentially contributing to the decreased quality of life commonly reported post-arrest. [7][8][9] Advanced knowledge of patient prognosis following a cardiac arrest is necessary to determine if resuscitation efforts are futile and ensure value-congruent care.…”