2022
DOI: 10.1186/s12887-022-03545-2
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The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis

Abstract: Background This study is a systematic review and meta-analysis on published studies about the Global Survival Rate of Graft and Patients in the Kidney Transplantation of children. Methods Studies that investigated the survival rate of kidney transplants published until the 30th of December 2020 were selected using a systematic search strategy in the following databases: Medline, Embase, Scopus, ProQuest, ISI Web of Science, and Cochrane. The extrac… Show more

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Cited by 8 publications
(2 citation statements)
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“…Over the years, serum creatinine testing has been the dominant method for monitoring the well-being of transplanted kidneys due to its widespread availability and familiarity [8]. Nevertheless, the stark reality remains that nearly 20% to 30% of kidney transplant patients experience allograft loss within five years of the surgical procedure, underscoring the urgent requirement for more effective monitoring tools and interventions [9,10].…”
Section: Introductionmentioning
confidence: 99%
“…Over the years, serum creatinine testing has been the dominant method for monitoring the well-being of transplanted kidneys due to its widespread availability and familiarity [8]. Nevertheless, the stark reality remains that nearly 20% to 30% of kidney transplant patients experience allograft loss within five years of the surgical procedure, underscoring the urgent requirement for more effective monitoring tools and interventions [9,10].…”
Section: Introductionmentioning
confidence: 99%
“…In the United States alone, over 200,000 people are now living with functioning kidney transplants, and rejection is the major cause for transplant loss ( 1 , 2 ). Although short-term graft survival is now excellent ( i.e ., 92% and 83% at 1 and 3 years respectively), the 10-year graft survival rate drops to ~60% due to a spectrum of allograft pathology with a variety of distinct mechanisms and therapeutic options ( 3 ). Timely diagnosis of pathology is imperative in preserving allograft longevity and has traditionally been achieved using conventional biopsy-based histologic methods.…”
Section: Introductionmentioning
confidence: 99%