The Gluten-Free Diet: Fad or Necessity?

Jones, Amy Little

doi:10.2337/ds16-0022

Cited by 55 publications

(54 citation statements)

References 32 publications

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“…1 However, celebrity/athletic endorsement of the GFD has cultivated an image of gluten as "unhealthy." 2 "Lifestylers," "free from," or "people who avoid gluten" are individuals who avoid gluten as a lifestyle choice. American market research 3,4 found that 44% of people buy gluten-free food for reasons other than GS, and that 65% believe that a GFD is generally healthier.…”

mentioning

confidence: 99%

“…5 The surge in gluten-free popularity has also encouraged an opposing belief that it is a "fad" diet. 2 This is unfortunate for people with CD/NCGS, who express that they are not taken seriously in restaurants, and even face dismissive attitudes from nonspecialist clinicians. 6 The drawing of a clear line between those who do and do not benefit from a GFD is needed to ground public and clinical perspective on these issues.…”

mentioning

confidence: 99%

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RETRACTED: Gluten Does Not Induce Gastrointestinal Symptoms in Healthy Volunteers: A Double-Blind Randomized Placebo Trial

et al. 2019

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confidence: 99%

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confidence: 99%

RETRACTED: Gluten Does Not Induce Gastrointestinal Symptoms in Healthy Volunteers: A Double-Blind Randomized Placebo Trial

et al. 2019

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“…Similarly to supermarket's own brands, gluten-free products are becoming more available and the trend is increasing [39]. Additionally, consumers often perceive gluten-free food as a healthier option [40]. However, concerns regarding the health aspects and nutritional qualities of gluten-free products have emerged in the scientific community [41].…”

Section: Introductionmentioning

confidence: 99%

A Comparison of the Nutritional Qualities of Supermarket’s Own and Regular Brands of Bread in Sweden

et al. 2020

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Processed food is associated with unhealthy qualities such as higher content of harmful fats, sugars and salt. The aim of our study was to compare the nutritional qualities of supermarket’s own brands and regular brands of bread sold in Sweden. Additionally, we compared the nutritional qualities of gluten-free and gluten-containing bread. We collected information from the labels of 332 bread products available in the largest grocery store chains. The Australian Health Star Rating (HSR) system was used to quantify the nutritional quality of each bread product. We compared all supermarket’s own brand products to regular brand products, and gluten-free to gluten-containing bread. The mean HSR for the supermarket’s own brands was lower than the regular brands (3.6 vs. 3.7; p = 0.046). For the regular brand products, the fibre, sugar and total fat content were greater (p < 0.001, p = 0.002 and p = 0.021, respectively), while less protein (p = 0.009) compared to regular bread products. Gluten-free bread had a lower HSR than gluten-containing bread (mean 3.5 vs. 3.8, respectively; p < 0.001). The regular brand products were slightly healthier than the supermarket’s own brands, primarily as a result of a higher fibre content. Gluten-free bread products were slightly unhealthier due to a lower protein content.

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“…The overlap of symptoms between NCGS and the more common IBS, together with the difficulty to establish a correct diagnosis of both these conditions, have generated a growing trend to adopt a gluten-free diet (GFD) in subjects with functional gastrointestinal symptoms [5]. The popularity of gluten-free products has grown disproportionately, as demonstrated by the worldwide increase in their sales estimated to reach US $7.59 billion by 2020 [6].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Non-Celiac Gluten Sensitivity in Patients with Previous Diagnosis of Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Crossover Trial

Barone

Gemello²,

Viggiani

et al. 2020

Nutrients

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Background. To date, there is no reliable marker for the diagnosis of non-celiac gluten sensitivity (NCGS), which benefits from a gluten-free diet (GFD). This condition is characterized by functional gastrointestinal symptoms similar to those occurring in the course of irritable bowel syndrome (IBS). However, IBS has a higher prevalence, and often benefits from the administration of a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet. The overlap of symptoms between these two pathologies has led to an overestimation of self-made diagnosis NCGS. Aims. To better identify NCGS in subjects with a previous diagnosis of IBS. Methods. All subjects received a low FODMAP diet that was also gluten-free (low FODMAP-GFD), and those presenting an improvement of symptoms were exposed to gluten or placebo (double-blind challenge with wash-out and crossover). The response to dietary treatments was evaluated by visual analogue scale (VAS). Results. Of 30 patients (23 women, seven men, aged 42.2 ± 12.5 years, body mass index (BMI) 24.7 ± 4.1 kg/m2), 26 benefited from the administration of low FODMAP-GFD and were exposed to the gluten/placebo challenge. After the challenge, using an increase of visual analogue scale VAS (Δ-VAS) ≥30%, 46.1% of the patients were NCGS+. However, this percentage became only 19.2% using a different method (mean ∆-VAS score plus two standard deviations). Conclusions. FODMAP intolerance could hide the response to a challenge test with gluten for the identification of NCGS in IBS patients. A low FODMAP-GFD followed by gluten/placebo challenge is able to identify patients with NCGS better. ClinicalTrials.gov registration number NCT04017585.

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The Gluten-Free Diet: Fad or Necessity?

Cited by 55 publications

References 32 publications

RETRACTED: Gluten Does Not Induce Gastrointestinal Symptoms in Healthy Volunteers: A Double-Blind Randomized Placebo Trial

RETRACTED: Gluten Does Not Induce Gastrointestinal Symptoms in Healthy Volunteers: A Double-Blind Randomized Placebo Trial

A Comparison of the Nutritional Qualities of Supermarket’s Own and Regular Brands of Bread in Sweden

Evaluation of Non-Celiac Gluten Sensitivity in Patients with Previous Diagnosis of Irritable Bowel Syndrome: A Randomized Double-Blind Placebo-Controlled Crossover Trial

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