The H+- and H+, K+-ATPases of the Collecting Duct

Cain, Brian D.; Gumz, Michelle L.; Zies, Deborah L.; Welch, Amanda

doi:10.1007/978-1-60327-229-2_10

Cited by 3 publications

(6 citation statements)

References 78 publications

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“…Anisotropy and other effects [77,96] should not be expected in this level of approximation. For r < 1, but not too small, according to [100,102,103,186], the transport coefficients from equation (10) are…”

Section: Stronger Dissipationmentioning

confidence: 99%

Towards dense, realistic granular media in 2D

Luding¹

2009

Nonlinearity

133

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The development of an applicable theory for granular matter -with both qualitative and quantitative value -is a challenging prospect, given the multitude of states, phases and (industrial) situations it has to cover. Given the general balance equations for mass, momentum, and energy, the limiting case of dilute and almost elastic granular gases, where kinetic theory works perfectly well, is the starting point.In most systems, low density coexists with very high density, where the latter is an open problem for kinetic theory. Furthermore, many additional non-linear phenomena and material properties are important in realistic granular media, involving, e.g.: (i) multi-particle interactions and elasticity (ii) strong dissipation, (iii) friction, (iv) long-range forces and wet contacts (v) wide particle size-distributions, and (vi) various particle shapes. Note that, while some of these issues are more relevant for high density, others are important for both low and high densities; some of them can be dealt with by means of kinetic theory, some can not. This paper is a review of recent progress towards more realistic models for dense granular media in 2D, even though most of the observations, conclusions, and corrections given are qualitatively true also in 3D. Starting from an elastic, frictionless and monodisperse hard sphere gas, the (continuum) balance equations of mass, momentum and energy are given. The equation of state, the (Navier-Stokes level) transport coefficients and the energy-density dissipation rate are considered. Several corrections are applied to those constitutive material laws -one by one -in order to account for the realistic physical effects and properties listed above.

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Section: Stronger Dissipationmentioning

confidence: 99%

Towards dense, realistic granular media in 2D

Luding¹

2009

Nonlinearity

133

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“…As in the diagram in Ref. 8, we omit ATP binding to the enzyme before the lumen-to-cytosol translocation. The assumptions made in Ref.…”

Section: Mathematical Model and Methodsmentioning

confidence: 99%

“…The assumptions made in Ref. 8 regarding ATP binding are based on the crystal structure and modus operandi of Ca 2ϩ -ATPase (38,39) and its homology to H ϩ -K ϩ -ATPase, both of which are part of the P-type ATPase family.…”

Section: Mathematical Model and Methodsmentioning

confidence: 99%

“…In addition, nongastric HKA was immunologically identified in macula densa (MD) cells of rabbits by Verlander et al (40). This isoform is highly expressed under K ϩ or Na ϩ deprivation (3,27) or under changes in acid-base balance, such as chronic metabolic acidosis (8,9,18). Moreover, studies have supported the idea that nongastric HKA plays a role in cellular Na ϩ homeostasis by extruding Na ϩ instead of H ϩ (9,10,17,29).…”

Section: Nadalmentioning

confidence: 96%

“…nongastric ATPase; H ϩ -K ϩ -ATPase; mathematical model; Na ϩ homeostasis; macula densa cell BOTH THE GASTRIC and nongastric or colonic isoforms of H ϩ -K ϩ -ATPase (HKA) are expressed in the kidney (15,18,45). Specifically, gastric HKA is mainly expressed in intercalated cells of both the collecting duct and connecting duct in rats (2,8,13). This isoform seems to be responsible for normal K ϩ reabsorption and H ϩ secretion that contribute to the maintenance of body K ϩ and acid-base balance.…”

Section: Nadalmentioning

confidence: 99%

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Parameter estimation for mathematical models of a nongastric H⁺(Na⁺)-K⁺(NH₄⁺)-ATPase

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Moore

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American Journal of Physiology-Renal Physiology

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Asymptomatic congenital Bronchial Pulmonary Arterial vascular malformation in an Adult.

Adhikari,

Giri,

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et al. 2023

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This case report describes a 41-year-old male patient whose screening chest X-ray revealed irregular tubular radio dense opacities in the right hilar region, suggestive of a vascular lesion. Subsequently, CT angiogram of the chest revealed a congenital bronchial artery-pulmonary artery fistula. Despite being informed about the diagnosis and available treatment options, the patient refused treatment and wanted to be on regular follow-up. This case highlights the importance of thorough imaging evaluation in diagnosing rare vascular abnormalities and explores the existing gap in literates regarding treatment in asymptomatic patients.

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The H+- and H+, K+-ATPases of the Collecting Duct

Cited by 3 publications

References 78 publications

Towards dense, realistic granular media in 2D

Towards dense, realistic granular media in 2D

Parameter estimation for mathematical models of a nongastric H⁺(Na⁺)-K⁺(NH₄⁺)-ATPase

Asymptomatic congenital Bronchial Pulmonary Arterial vascular malformation in an Adult.

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The H+- and H+, K+-ATPases of the Collecting Duct

Cited by 3 publications

References 78 publications

Towards dense, realistic granular media in 2D

Towards dense, realistic granular media in 2D

Parameter estimation for mathematical models of a nongastric H+(Na+)-K+(NH4+)-ATPase

Asymptomatic congenital Bronchial Pulmonary Arterial vascular malformation in an Adult.

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Parameter estimation for mathematical models of a nongastric H⁺(Na⁺)-K⁺(NH₄⁺)-ATPase