The Healing Effect Of Hyperium Perforatum (St. John’s Wort) On Experimental Alcaline Corrosive Eosephageal And Stomach Burns

Güvenç, Erkan; Kıyan, Selahattin; Uyanıkgil, Yiğit; Çetin, Emel Öykü; Karabey, Fatih; Çavuşoğlu, Türker; Gökçe, Burak

doi:10.14744/tjtes.2019.93428

Ulus Travma Acil Cerrahi Derg

2019

DOI: 10.14744/tjtes.2019.93428

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The Healing Effect Of Hyperium Perforatum (St. John’s Wort) On Experimental Alcaline Corrosive Eosephageal And Stomach Burns

Erkan Güvenç¹,

Selahattin Kıyan

Yiğit Uyanıkgil

et al.

Abstract: BACKGROUND:The most frequent etiologic cause is alkaline substances. We investigated the protective effects of the plant St. John 's Wort (Hypericum perforatum).

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2024

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Healing Effect of Hypericum perforatum in Burn Injuries

Hamedi,

Manafi,

Hashemi

et al. 2024

WJPS

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Background: Burn injury is still the leading cause of mortality and morbidity in burn patients. We comapred healing effect of Hypericum perforatum , silver sulfadiazine and alpha ointments on burn injuries in rat model. Methods: Sixty female Sprague-Dawley rats in an animal experimental study were randomly divided to 5 equal groups as H. perforatum , silver sulfadiazine and (SSD), alpha, gel base and the burn injury left untreated. Wounds were assessed macroscopically and histologic after burn injury and on days 7 th , 14 th and 21 st after treatments. Results: Burn wounds decreased in size on day 7 th in H. perforatum group ( P <0.01). Regarding scoring the inflammation, re-epithelialization, angiogenesis, formation of granulation tissue and number of macrophage, the best scores were visible in H. perforatum group, and the worst in the gel base and the burn injury left untreated ( P <0.01). Conclusions: H. perforatum was shown to significantly induce re-epithelialization, angiogenesis and granulation tissue and decrease the inflammation resulting into a healing process in burn wounds. As H. perforatum is inexpensive and an easily available herbal medicine, it can be considered as a therapeutic of choice to ameliorate burn injuries.

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Healing Effect of Hypericum perforatum in Burn Injuries

Hamedi,

Manafi,

Hashemi

et al. 2024

WJPS

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The Healing Effect Of Hyperium Perforatum (St. John’s Wort) On Experimental Alcaline Corrosive Eosephageal And Stomach Burns

Abstract: BACKGROUND:The most frequent etiologic cause is alkaline substances. We investigated the protective effects of the plant St. John 's Wort (Hypericum perforatum).

Cited by 1 publication

References 44 publications

Healing Effect of Hypericum perforatum in Burn Injuries

Healing Effect of Hypericum perforatum in Burn Injuries

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