The heat is on: the impact of excessive temperature increments on complications of laser treatment for ureteral and renal stones

Abstract

Objective Technological advancements in the field of urology have led to a paradigm shift in the management of urolithiasis towards minimally invasive endourological interventions, namely ureteroscopy and percutaneous nephrolithotomy. However, concerns regarding the potential for thermal injury during laser lithotripsy have arisen, as studies have indicated that the threshold for cellular thermal injury (43 °C) can be exceeded, even with conventional low-power laser settings. This review aims to identify the factors that contribute to temperature increments during laser treatment using current laser systems and evaluate their impact on patient outcomes. Materials and methods To select studies for inclusion, a search was performed on online databases including PubMed and Google Scholar. Keywords such as 'temperature' or 'heat' were combined with 'lithotripsy', 'nephrolithotomy', 'ureteroscopy', or 'retrograde intrarenal surgery', both individually and in various combinations. Results Various strategies have been proposed to mitigate temperature rise, such as reducing laser energy or frequency, shortening the duration of laser activation, increasing the irrigation fluid flow rate, and using room temperature or chilled water for irrigation. It is important to note that higher irrigation fluid flow rates should be approached cautiously due to potential increases in intrarenal pressure and associated infectious complications. The utilization of a ureteral access sheath (UAS) may offer benefits by facilitating irrigation fluid outflow, thereby reducing intrapelvic pressure and intrarenal fluid temperature. Conclusion Achieving a balance between laser power, duration of laser activation, and irrigation fluid rate and temperature appears to be crucial for urologists to minimize excessive temperature rise.

The Effect of Laser Settings and Ureteral Access Sheath Size on Intrapelvic Temperature during Holmium Laser Lithotripsy

“…Up to now, published results of experimental studies on animals and in vitro models have focused on the impact of various laser powers settings and the type of irrigation system used on changes in IPT. The use of a ureteral access sheath may offer benefits by facilitating irrigation fluid outflow, thus lowering intrapelvic pressure and decreasing intrarenal fluid temperature [16]. But the issue of how the size of the UAS affects temperature remains a considerably less explored topic.…”