The helical flow pump with a hydrodynamic levitation impeller

Abe, Yusuke; Ishii, Kohei; Igarashi, Takashi; Saito, Itsuro; Inoue, Yusuke; Ono, Takahiro; Nakagawa, Hidemoto; Emiko, Nakano; Fukazawa, Kyoko; Ishihara, Kazuhíko; Fukunaga, Kazuyoshi; Ōno, Minoru; Imachi, Kou

doi:10.1007/s10047-012-0659-z

Cited by 20 publications

(18 citation statements)

References 30 publications

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“…The results indicated that the HFP has a novel and quite unique working principle. Reported favorable features of the HFP, such as high performance with low rotational speed [8], a good antithrombogenic property [8] and great pulsatility [9] are the advantages of this working principle.…”

Section: Discussionmentioning

confidence: 97%

“…In the HFP, as acceleration of the vortexes was not Artif Organs remarkable, so the pumping principle is different from that of the cascade pump. The HFP was invented by transforming the compressor of turbine engine [8]. When the rotating impeller rotates the fluid, the fluid moves from the inlet side to the outlet side.…”

Section: Discussionmentioning

confidence: 99%

“…In the RBP-based TAH, some pulsatility is necessary to prevent sucking of atria that induces sudden lung edema and circulatory failure [7]. The helical flow pump (HFP) was invented to be an ideal pump for developing the TAH [8]. The HFP has inlet and outlet ports at the same radial side and can generate the complete pulsatile flow in the range of heart rate from 60 to 120 BPM [9].…”

Section: Introductionmentioning

confidence: 99%

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Hydrodynamic characteristics of the helical flow pump

et al. 2015

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The helical flow pump (HFP) was invented to be an ideal pump for developing the TAH and the helical flow TAH (HFTAH) using two HFPs has been developed. However, since the HFP is quite a new pump, hydrodynamic characteristics inside the pump are not clarified. To analyze hydrodynamic characteristics of the HFP, flow visualization study using the particle image velocimetry and computational fluid dynamics analysis were performed. The experimental and computational models were developed to simulate the left HFP of the HFTAH and distributions of flow velocity vectors, shear stress and pressure inside the pump were examined. In distribution of flow velocity vectors, the vortexes in the vane were observed, which indicated that the HFP has a novel and quite unique working principle in which centrifugal force rotates the fluid in the helical volutes and the fluid is transferred from the inlet to the outlet helical volutes according to the helical structure. In distribution of shear stress, the highest shear stress that was considered to be occurred by the shunt flow across the impeller was found around the entrance of the inlet helical volute. However, it was not so high to cause hemolysis. This shunt flow is thought to be improved by redesigning the inlet and outlet helical volutes. In distribution of pressure, negative pressure was found near the entrance of the inlet helical volute. However, it was not high. Negative pressure is thought to be reduced with an improvement in the design of the impeller or the vane shape.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Hydrodynamic characteristics of the helical flow pump

et al. 2015

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“…Abe et al [17] said that pulsatile flow might reinflate such a deflation during the atrial diastolic phase and thus avoid the fatal sucking effect. For 1/R control, the parameters of AoP, LAP, and RAP need to be measured with pressure sensors.…”

Section: Discussionmentioning

confidence: 99%

Hemodynamics of a functional centrifugal-flow total artificial heart with functional atrial contraction in goats

et al. 2015

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Implantation of a total artificial heart (TAH) is one of the therapeutic options for the treatment of patients with end-stage biventricular heart failure. There is no report on the hemodynamics of the functional centrifugal-flow TAH with functional atrial contraction (fCFTAH). We evaluated the effects of pulsatile flow by atrial contraction in acute animal models. The goats received fCFTAH that we created from two centrifugal-flow ventricular assist devices. Some hemodynamic parameters maintained acceptable levels: heart rate 115.5 ± 26.3 bpm, aortic pressure 83.5 ± 10.1 mmHg, left atrial pressure 18.0 ± 5.9 mmHg, pulmonary pressure 28.5 ± 9.7 mmHg, right atrial pressure 13.6 ± 5.2 mmHg, pump flow 4.0 ± 1.1 L/min (left) 3.9 ± 1.1 L/min (right), and cardiac index 2.13 ± 0.14 L/min/m(2). fCFTAH with atrial contraction was able to maintain the TAH circulation by forming a pulsatile flow in acute animal experiments. Taking the left and right flow rate balance using the low internal pressure loss of the VAD pumps may be easier than by other pumps having considerable internal pressure loss. We showed that the remnant atrial contraction effected the flow rate change of the centrifugal pump, and the atrial contraction waves reflected the heart rate. These results indicate that remnant atria had the possibility to preserve autonomic function in fCFTAH. We may control fCFTAH by reflecting the autonomic function, which is estimated with the flow rate change of the centrifugal pump.

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“…Consequently, it needs four parameters, QL, AoP, LAP and RAP. Currently, in our helical flow TAH (HFTAH) [10] using helical flow pumps [11], we are using electro-magnetic flow probes and pressure transducers to acquire data of the four parameters to run the 1/R control logic. However, these sensors are too big to be implanted in the body and thus require skinpenetrating pressure lines and cables.…”

Section: Introductionmentioning

confidence: 99%

Concept of left atrial pressure estimation using its pulsatile amplitude in the helical flow total artificial heart

Saito

Igarashi

et al. 2014

J Artif Organs

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The total artificial heart (TAH) requires physiological control to respond to the metabolic demand of the body. To date, 1/R control is a single physiological control method that can control venous pressure. To realize an implantable 1/R control system, we are developing a new pressure measuring method using absolute pressure sensor. To find a method for absolute pressure sensor, which went well without calibration, concept of left atrial pressure (LAP) estimation using its pulsatile amplitude was proposed. Its possibility was investigated with two long-term survived goats whose hearts were replaced with the helical flow TAHs. In manual control condition, there existed a positive relation between mean LAP (mLAP) and normalized pulsatile amplitude (NPA). Percent systole revealed not to affect the relationship between mLAP and NPA. Dispersion was observed between different pulse rates. As for cardiac output difference (QLD) that is the difference of flow rate between systolic and diastolic phases, similar results were obtained except in low QLDs. In the 1/R control condition, relatively high correlation between mLAP and NPA could be obtained. In estimation of mLAP using the correlating function of individual goat, fairly good correlation was obtained between measured mLAP and estimated mLAP. Despite that further studies are necessary, it was demonstrated that the concept of the LAP estimation could be possible.

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The helical flow pump with a hydrodynamic levitation impeller

Cited by 20 publications

References 30 publications

Hydrodynamic characteristics of the helical flow pump

Hydrodynamic characteristics of the helical flow pump

Hemodynamics of a functional centrifugal-flow total artificial heart with functional atrial contraction in goats

Concept of left atrial pressure estimation using its pulsatile amplitude in the helical flow total artificial heart

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