The Histologist's Role in the Diagnosis and Management of Chronic Hepatitis B and C

Distance between the substrate and regulatory reduced coenzyme binding sites of bovine liver glutamate dehydrogenase by resonance energy transfer

“…Either NADPH or NADH is capable of binding to the catalytic site [9] and high concentrations of these coenzymes inhibit the enzyme by binding to a distinct reduced coenzyme regulatory site [lo]. ADP, which activates the enzyme, has two binding sites per subunit [Ill.…”