The Histology of Eccrine Poromas: A Study of 14 Cases

Abstract

A histological study of 14 eccrine poromas in 14 different patients was conducted and the results correlated with the clinical data. Histologically, an eccrine poroma is an easily recognizable epithelial skin tumor. Three morphological variants can be identified: a benign, a premalignant or dysplastic, and an invasive, malignant form. These tumors hardly have a typical clinical appearance. Symptoms such as bleeding, pain and itching are suggestive of a possible malignant transformation. There seems to be a predilection for localization on the limbs and the head. Most of the lesions occur in patients above the age of 60. It is noteworthy that these tumors, at least those of the face, occur on actinically damaged areas.

Benign eccrine poroma of neck: an unusual presentation

“…And benign poroma form less than 10% of these making it a highly uncommon diagnosis. 8 It is generally found on acral locations, but can be found on almost any cutaneous surface.…”

A Case of an Unusual Eccrine Poroma on the Left Forearm Area

“…However, eccrine poroma has been rarely reported on the forearm. The pathogenesis is unknown, but actinic damage, radiation, trauma and the human papilloma virus have been implicated [5][6][7][8] .…”

“…Although eccrine poroma is known to be benign, the variants of eccrine poroma seem to frequently have malignant features. Pylyser et al 7 reported that almost 50% of eccrine poromas exhibited malignant biological behaviors, and Robson et al 9 reported that coexistence between benign eccrine poroma and eccrine porocarcinoma is encountered in up to 11% of the cases. Importantly, the bleeding tendency without pain or itching has not been recognized as the hall marker of malignant transformation.…”

“…Witkowski et al 12 reported that the lesion should be excised completely as recurrence tended to be common after partial removal. Pylyser et al 7 found that with total excision, the benign lesion was fully cured and the prognosis was good for the malignant variant when making a timely diagnosis and performing wide excision of the lesion. In this study, we reported on an unusual benign eccrine poroma that showed some malignant features and an infiltrative growth pattern like eccrine porocarcinoma, and this tumor occurred at a rare site, the left forearm.…”

Porocarcinome eccrine

“…Depuis la première description de Smith et Coburn [15] en 1956 sous l'appellation d'hidroacanthome malin, de rares cas de po rocarcinome ont été rapportés isolément [1][2][3][4][5]7,8,[10][11][12][13]15,16]. Récemment, la lit térature s'est enrichie d'une série de 27 cas rapportés par Schaw et al [14] et de 18 cas par Mehregan et al [9].…”