The History of Bone Grafts

Boer, H H de

doi:10.1097/00003086-198801000-00037

Cited by 136 publications

(116 citation statements)

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“…There are several materials available for restoration of these defects like autogenous free bone grafts, vascularised bone grafts, pedicled grafts, allografts, xenografts and alloplasts [15][16][17][18][19]. Autogenous grafts remain the gold standard in reconstruction of such defects.…”

Section: Discussionmentioning

confidence: 99%

Cranioplasty of Hemispherical Defects Using Calcium Phosphate Cements Along with Titanium Mesh: Our Experience

Kumar

Sudeep

Balwan

2015

J. Maxillofac. Oral Surg.

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Introduction Cranial defects may arise due to trauma, infection, surgical ablation or errors in development. Restoration of such defects is important for esthetics, function and morale of the patient. Several materials are available. Each has its advantages and disadvantages. Search is on for an ideal material. Autogenous grafts remain the gold standard in reconstruction of such defects. However, the morbidity associated with their harvest, additional time required, the need for a second surgical site and the limited supply has led to the search for newer substitutes. Although many materials are available today including biologic and non biologic substitutes, there is still no consensus about the best material. In this article we describe our use of calcium phosphate cements for reconstruction of hemispherical cranial defects. Materials and Methods Cases requiring reconstruction of hemispherical cranial defects (more than 15 cm in any dimension) were selected for study. After exposing the defect under GA, titanium mesh was adapted to the defect for support. Then the calcium phosphate cement was prepared and injected on the mesh to establish good contour. The alloplastic insert in each patient was evaluated for: (a) Immediate post-operative complications (b) Restoration of contour and soft tissue support (c) New bone formation ascertained on HRCT at the end of 2 years. Patients were examined on postoperative first week, at 3 and at 6 months.High resolution computed tomography scans were taken at 2 years postop. There were two female and three male patients. Results There were no complications in the post operative period. The general condition of the patients improved post operatively. Even though the cements maintained their contour at 2 years, there were no signs of bone formation within the cement. Conclusion Calcium phosphate cement is a good bone substitute for use in cranioplasty. In defects requiring mechanical strength, it should be supported by a titanium mesh. It retains the contour but is not replaced by bone even after 2 years.

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Section: Discussionmentioning

confidence: 99%

Cranioplasty of Hemispherical Defects Using Calcium Phosphate Cements Along with Titanium Mesh: Our Experience

Kumar

Sudeep

Balwan

2015

J. Maxillofac. Oral Surg.

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“…Antibiotisch beladene Knochenchips wurden erstmals lokal zur Behandlung einer Osteomyelitis eingesetzt und dabei mit Penicillin kombiniert [14,54,63]. Inzwischen gibt es zahlreiche Berichte über eine erfolgreiche Infektsanierung und Auffüllung von Knochendefekten im Zuge einer Osteomyelitistherapie durch Verwendung von allogenem spongiösen Knochenmaterial, das wahlweise mit verschiedenenAntibiotika imprägniertwur-de [70].…”

Section: Autologes Oder Allogenes Knochentransplantatunclassified

Lokale Antibiotikatherapie

2017

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“…The operation was successful but, because an animal graft was being used on a Christian, there were religious repercussions, and the soldier was excommunicated. The success of the operation was testified by the fact that when the soldier asked the surgeon to remove the fragment so that he could be readmitted into the church, the fragment had been fully incorporated (De Boer 1988).…”

Section: Historical Descriptionmentioning

confidence: 99%

“…The concepts of bone callus, implant and resorption began to be outlined. In 1743, Duhamel published the results of his experiments on animals and suggested that the periosteum has a pivotal role in the process of osteogenesis (De Boer 1988, Glicenstein 2000. Most operations requiring bone resection were for nonunion, which was often treated by amputating the limb.…”

Section: Historical Descriptionmentioning

confidence: 99%

“…In that publication, cited by Putti in 1912 as "an immortal work on bone generation", Ollier maintained that "implanted bone fragments are viable if they include the periosteum, which is the most important viability factor of the graft" (Putti 1912, De Boer 1988. Ollier achieved an authoritative position with his theories and opened the way for complex experimental and clinical observations in bone grafting.…”

Section: Historical Descriptionmentioning

confidence: 99%

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