The History of Surgical Research

Picichè, Marco

doi:10.1007/978-88-470-2400-7_2

Cited by 4 publications

(3 citation statements)

References 11 publications

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“…Currently, the IMDs have been implanted in various parts of human body as artificial treatments and diagnostic tools, including sensors, pacemakers, implantable cardioverter defibrillators, cochlear implant and stimulators for deep brain, nerve and bone 1. These implantable electronic devices can provide diagnosis (e.g.…”

Section: Introductionmentioning

confidence: 99%

Recent Progress on Piezoelectric and Triboelectric Energy Harvesters in Biomedical Systems

et al. 2017

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Implantable medical devices (IMDs) have become indispensable medical tools for improving the quality of life and prolonging the patient's lifespan. The minimization and extension of lifetime are main challenges for the development of IMDs. Current innovative research on this topic is focused on internal charging using the energy generated by the physiological environment or natural body activity. To harvest biomechanical energy efficiently, piezoelectric and triboelectric energy harvesters with sophisticated structural and material design have been developed. Energy from body movement, muscle contraction/relaxation, cardiac/lung motions, and blood circulation is captured and used for powering medical devices. Other recent progress in this field includes using PENGs and TENGs for our cognition of the biological processes by biological pressure/strain sensing, or direct intervention of them for some special self‐powered treatments. Future opportunities lie in the fabrication of intelligent, flexible, stretchable, and/or fully biodegradable self‐powered medical systems for monitoring biological signals and treatment of various diseases in vitro and in vivo.

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Section: Introductionmentioning

confidence: 99%

Recent Progress on Piezoelectric and Triboelectric Energy Harvesters in Biomedical Systems

et al. 2017

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“…Initial studies on ITA-related NCCMBF - Prior to the first successful on-pump open heart operation by Gibbon in 1953 [ 79 - 81 ], and the global spread of coronary surgery in the 1960s and 1970s [ 46 , 82 ], myocardial revascularization was achieved through ingenious and heterogeneous techniques [ 46 - 54 , 83- 85 ]. Early research in the US by Claude S. Beck demonstrated that the heart could be revascularized by neovessels developed within artificially created pericardial adhesions [ 46 - 49 , 86, 87 ].…”

Section: The Itas’ Potential For Developing Collateral Branchesmentioning

confidence: 99%

Noncoronary Collateral Myocardial Blood Flow: The Human Heart’s Forgotten Blood Supply

Picichè

2015

TOCMJ

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The “noncoronary collateral circulation” (NCCC) or “noncoronary collateral myocardial blood flow” (NCCMBF), reaches the heart through a micro-vascular network arising from the bronchial, esophageal, pericardial, diaphragmatic, and aortic arteries. The left and right internal thoracic arteries (ITAs) along with their collateral branches also serve as a source of NCCMBF-a feature seen in other mammals. Under certain circumstances the ITAs have a high potential for developing collateral branches. In the case of severe Leriche syndrome or with chronic obstruction of the abdominal aorta, the ITAs can serve as the main or even sole source of blood supply to the lower limbs. It is also possible for the ITAs to develop angiographically visible branches that directly connect with the coronary arteries. In ischemic conditions there is a functional, ischemia-reducing extracardiac coronary artery supply via natural ipsilateral ITA anastomosis. To date we know little about NCCMBF and its potential benefits in clinical applications, which makes this a challenging and intriguing field of research. This paper reviews all available data on noncoronary collateral blood supply to the human heart.

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“…This brought about the concept of randomized controlled trials which were considered to be more reliable and reproducible than observational studies, had data sets that were preconstructed, randomized patients to theoretically remove selection bias, and had power in the studies to prove a hypothesis [1]. The perplexing question in reference to treating individual patients is how to take these data either from a randomized prospective trial or a longitudinal registry, even a large single series experience, and apply them to your patient’s present condition.…”

Section: Introductionmentioning

confidence: 99%

Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient

Shah

Darling

2018

Gefässchirurgie

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Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic centers. We use RCTs to help explain the rational for intervention and then rely on longitudinal registries and single center data to give the patients a real-world expectation concerning outcomes and complications in our hands.

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The History of Surgical Research

Cited by 4 publications

References 11 publications

Recent Progress on Piezoelectric and Triboelectric Energy Harvesters in Biomedical Systems

Recent Progress on Piezoelectric and Triboelectric Energy Harvesters in Biomedical Systems

Noncoronary Collateral Myocardial Blood Flow: The Human Heart’s Forgotten Blood Supply

Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient

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