The HIV-1 Epidemic: Low- to Middle-Income Countries

Shao, Yiming; Williamson, Carolyn

doi:10.1101/cshperspect.a007187

Cited by 103 publications

(87 citation statements)

References 82 publications

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“…This distribution is very dynamic, progressive and unpredictable; it will continue to diversify as long as the virus circulates [1]- [7]. There is a very large genetic diversity of this group M in the DRC and particularly in Kinshasa [1]- [7]. The subtype B, which is the dominant one in Western Europe and North America has a prevalence <1% in Kinshasa [1].…”

Section: Backgroundsmentioning

confidence: 99%

“…The distribution of this group in Africa and the Democratic Republic of Congo (DRC), in particular, is very heterogeneous; it follows a complex and specific algorithm [1]- [7]. This distribution is very dynamic, progressive and unpredictable; it will continue to diversify as long as the virus circulates [1]- [7]. There is a very large genetic diversity of this group M in the DRC and particularly in Kinshasa [1]- [7].…”

Section: Backgroundsmentioning

confidence: 99%

“…Group M (Major) is the dominant group in Central Africa [1]- [7]. The distribution of this group in Africa and the Democratic Republic of Congo (DRC), in particular, is very heterogeneous; it follows a complex and specific algorithm [1]- [7]. This distribution is very dynamic, progressive and unpredictable; it will continue to diversify as long as the virus circulates [1]- [7].…”

Section: Backgroundsmentioning

confidence: 99%

“…The classification of types, groups, subgroups, sub-groups and different recombinant forms (CRFs-Circulating Recombinant Forms) or mutant allowed better understanding the virus, its geographical distribution and the evolution of the epidemic [1]- [7]. It also helped direct the management of patients infected by HIV [1]- [7]. Group M (Major) is the dominant group in Central Africa [1]- [7].…”

Section: Backgroundsmentioning

confidence: 99%

“…It also helped direct the management of patients infected by HIV [1]- [7]. Group M (Major) is the dominant group in Central Africa [1]- [7]. The distribution of this group in Africa and the Democratic Republic of Congo (DRC), in particular, is very heterogeneous; it follows a complex and specific algorithm [1]- [7].…”

Section: Backgroundsmentioning

confidence: 99%

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Involvement of the Genetic Diversity of HIV-1 in the Virological Treatment Failure of First Line Antiretroviral in Kinshasa

Kamangu¹,

Kalala²,

Mvumbi³

et al. 2017

WJA

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Background: Genetic diversity of human immunodeficiency virus affects the treatment and the emergence of resistance. Some subtypes would develop resistance more frequently than others. The aim of this study is to determine the rate of virological treatment failure and the involvement of genetic diversity and different mutations in this failure in Kinshasa. Methods: Of the 153 Antiretroviral-naive patients who were included in the cohort, 138 patients have been received for the appointment of the 6 th month. Clinical parameters were

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Section: Backgroundsmentioning

confidence: 99%

Section: Backgroundsmentioning

confidence: 99%

Section: Backgroundsmentioning

confidence: 99%

Section: Backgroundsmentioning

confidence: 99%

Section: Backgroundsmentioning

confidence: 99%

See 3 more Smart Citations

Involvement of the Genetic Diversity of HIV-1 in the Virological Treatment Failure of First Line Antiretroviral in Kinshasa

Kamangu¹,

Kalala²,

Mvumbi³

et al. 2017

WJA

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Is “Undetectable = Untransmissible” Good Public Health Messaging?

Tan

Lim

Chan³

2021

AMA Journal of Ethics

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This article considers merits and drawbacks of "undetectable = untransmissible" (U = U) messaging in the global HIV response. First, viral suppression might be achieved with effective treatment, but not everyone living with HIV has access to such intervention and care. Second, although U = U can help individuals living with HIV, this messaging might stigmatize those for whom interventions have not achieved viral suppression. Third, although biomedical advances have attempted to address infectiousness, syndemic drivers that predispose individuals to HIV acquisition are not well accounted for by U = U messaging.To claim one AMA PRA Category 1 Credit TM for the CME activity associated with this article, you must do the following: (1) read this article in its entirety, (2) answer at least 80 percent of the quiz questions correctly, and (3) complete an evaluation. The quiz, evaluation, and form for claiming AMA PRA Category 1 Credit TM are available through the AMA Ed Hub TM .

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