“…Several investigators, including Braithwaite " and Abernathy," suggest an endocrine basis for this con¬ dition. Braithwaite found vague resemblances to mongolism in his patient, and because his "mongol" had a shallow sella turcica (as hypertelorism occasionally does) 4 he suggested a dyspituitarism as the common lesion in the two ; also in his experience pituitary therapy had been somewhat useful. Certainly this is nothing more than a theory.…”
Section: Etiology and Pathologymentioning
confidence: 91%
“…This patient possibly showed for the first time in the literature the combination of the three classic signs-family tendency, orbital separation and retarded mentality. 4. It is more correct to refer to family tendency than to heredity in this condition.…”
Section: Diagnosis Prognosis and Treatmentmentioning
Hypertelorism is probably more common than reports indicate, and many readers may recall characteristic facies in their clinical experience. Reported cases are,
“…Several investigators, including Braithwaite " and Abernathy," suggest an endocrine basis for this con¬ dition. Braithwaite found vague resemblances to mongolism in his patient, and because his "mongol" had a shallow sella turcica (as hypertelorism occasionally does) 4 he suggested a dyspituitarism as the common lesion in the two ; also in his experience pituitary therapy had been somewhat useful. Certainly this is nothing more than a theory.…”
Section: Etiology and Pathologymentioning
confidence: 91%
“…This patient possibly showed for the first time in the literature the combination of the three classic signs-family tendency, orbital separation and retarded mentality. 4. It is more correct to refer to family tendency than to heredity in this condition.…”
Section: Diagnosis Prognosis and Treatmentmentioning
Hypertelorism is probably more common than reports indicate, and many readers may recall characteristic facies in their clinical experience. Reported cases are,
“…4 Since then not only has our own experience been extended but also the personal communications we have received from other labora¬ tories which are using this modification have been so encouraging that we feel the method deserves wider usage. Furthermore, the recent article by Schneider,5 in which he reports 100 cases using, as have we, the rabbit as the test animal, further demonstrates the practical value of this particular method.…”
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