The human gallbladder

Luciano, L.; Reale, E.

doi:10.1007/978-1-4613-0869-0_12

Cited by 7 publications

(5 citation statements)

References 48 publications

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“…In the apical region, secretory granules can be observed with an electrondense content; however, in non-osmicated tissue they are electron-lucent. Mitochondria are abundant and frequently flanked by small, flattened cisternae of the rough endoplasmic reticulum, dense bodies and secretory granules (Gilloteaux et al, 1989;Luciano and Reale, 1990;Luciano et al, 1973;Pemsingh et al, 1987a).…”

Section: Introductionmentioning

confidence: 99%

Characterization of glycoproteins in the epithelial cells of human and other mammalian gallbladder: A review

Madrid

Hernández

Ballesta

1997

Microsc. Res. Tech.

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Section: Introductionmentioning

confidence: 99%

Characterization of glycoproteins in the epithelial cells of human and other mammalian gallbladder: A review

Madrid

Hernández

Ballesta

1997

Microsc. Res. Tech.

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“…This corroborated female preponderance of gallbladder cancer noted in national and international reports. [3,[11][12][13] Alatise et al [12] in Nigeria documented a male-to-female ratio of 1:7 and George et al [3] in India reported a male-tofemale ratio of 2:5. The reason for this pattern has been linked to female sex hormones.…”

Section: Discussionmentioning

confidence: 99%

“…Further, gallbladder cancer is reportedly associated with high parity, although the role of oestrogen receptor and progesterone receptor expression may not be significantly different between men and women. [3,6,[11][12][13] Gallbladder carcinoma typically manifests as focal intraluminal mass, focal or diffuse wall thickening, and gallbladder replaced by the mass. The mass usually has a low attenuation with variable enhancement, most commonly irregular peripheral enhancement.…”

Section: Discussionmentioning

confidence: 99%

“…The thickness of the wall varies with the degree of distension and is usually less than 3mm in diameter. [13] Early detection and diagnosis of gallbladder carcinoma are difficult because most patients present with non-specific findings of right upper quadrant pain, malaise, weight loss, jaundice, anorexia, and vomiting. [6] However, the risk is higher in those with chronic inflammation following cholelithiasis.…”

Section: Introductionmentioning

confidence: 99%

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Pattern of Computerized Tomographic Findings in Suspected Gallbladder Cancer in Nigeria

Olusola-Bello¹,

Olatunji²,

Ajayi³

et al. 2021

Ann Health Res

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Background: Gallbladder (GB) cancer is a rare malignancy with a variable incidence worldwide. Imaging detection at an early stage is elusive. Preoperative imaging for tumour recognition and non-invasive staging is essential to triage patients to appropriate care. Objectives: To describe the CT imaging findings of GB cancer among Nigerians. Methods: A retrospective review of the CT images of 15 patients who had gall bladder carcinoma between January 2015 and June 2017 at a private diagnostic facility in Lagos was done. Results: The age of the patients ranged from 39 to 73 years with a mean age of 60.9 years. The male to female ratio was 1:4.3. Clinical presentations included abdominal pain (61.5%) and jaundice (38.5%). Irregular GB wall thickening (61.5%) and focal mass lesions in the GB (38.5%) were the main features on imaging while 38.5% had associated gall stones. Infiltration of the adjacent liver was found in 76.9% and 60 % of those who had local infiltration of the liver also had intrahepatic metastasis. Conclusion: A majority of gall bladder cancer cases are still diagnosed in their late stages. CT scan readily delineates regional spread into adjacent organs which may be obscured in other imaging modalities due to adjacent bowel gas.

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“…Literature sources present descriptions of gallbladder microstructure, especially the structures responsible for its functions, that is, cylindrical epithelium, specialized in the processes of absorption and transport of water, as well as complex subepithelial glands. These structures, which thickens mucus and enriches bile were described in carnivores, rodents, and humans (Azalli, 1993;Halley-Russel, 1989;Hayward, 1962;Jackowiak and Godynicki, 2006;Koga, 1973;Luciano and Reale, 1990;McPherson et al, 1983;Strombeck, 1979).…”

Section: Introductionmentioning

confidence: 88%

Angioarchitecture of gallbladder in pig: LM and SEM study on vascular microcorrosion casts

Prozorowska

Jackowiak

2014

Microsc. Res. Tech.

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The study focused on the description of pig gallbladder angioarchitecture, with particular emphasis on the specifics of the course of blood vessels in individual layers of the gallbladder wall. Furthermore, the vascular systems of the pig gallbladder were analyzed in terms of the adaptation of this organ to changes in its volume during cyclical bile storage and discharge. The gallbladder is supplied by the cystic artery, which in the pig represents a mixed pinnate and bipinnate pattern of branching. The light microscopic and scanning electron microscopic observations of three-dimensional vascular corrosion casts showed the presence of two main complex vascular networks in the wall of the gallbladder, one located in the subserosal and the other in the mucosa. The unique features in the pig, connected with the size of the gallbladder, is the well-developed horizontal venous plexus under folds of the mucosa, which is a voluminous reservoir of fluids absorbed from bile and vascular networks around mucous glands. Superficial blood vessels of the gallbladder run in vascular pairs or triads, where a single artery runs between two veins. The structures of blood flow control, that is, venous valves, were observed only in venules of the subserosal plexus. Spatial arrangement of the vascular network in the pig gallbladder shows functional plasticity during changes in gallbladder volume. The course of superficial blood vessels in the well-filled gallbladder is arcuate, while in the empty gallbladder it is undulated or spiral. In the mucosal and intramural vessels the direction of blood vessels may change from perpendicular to oblique.

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The human gallbladder

Cited by 7 publications

References 48 publications

Characterization of glycoproteins in the epithelial cells of human and other mammalian gallbladder: A review

Characterization of glycoproteins in the epithelial cells of human and other mammalian gallbladder: A review

Pattern of Computerized Tomographic Findings in Suspected Gallbladder Cancer in Nigeria

Angioarchitecture of gallbladder in pig: LM and SEM study on vascular microcorrosion casts

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