The Icare-Pro Rebound Tonometer Versus the Hand-held Applanation Tonometer in Congenital Glaucoma

Sanz, Lara Borrego; Morales-Fernández, Laura; de-la-Casa, Jose M. Martínez; Sáenz-Francés, F.; Fuentes, Manuel; García‐Feijoó, Julián

doi:10.1097/ijg.0000000000000177

Cited by 26 publications

(24 citation statements)

References 31 publications

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“…Our finding of lower IOP readings with the Icare PRO contrasts with results from some previous studies in children, 6 7 8 which have reported a tendency for similar or higher measurements with the Icare PRO. Higher IOP measurements with the Icare PRO compared to applanation tonometry have also been reported for supine adults.…”

Section: Discussioncontrasting

confidence: 99%

“…Some studies that compare the Icare PRO to other tonometers in supine children suggest Icare measurements tend to be slightly higher or the same as other tonometers. 6 7 8 However, these studies are rare and have typically evaluated data from a Western population. 6 7 8 The purpose of this study is to compare IOP measurements with Icare PRO to measurements by two applanation devices (the Tono-Pen XL and Pneumotonometer Model 30 classic; both by Reichert, Buffalo, NY, USA) in supine children with glaucoma.…”

Section: Introductionmentioning

confidence: 99%

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A comparison of rebound to indentation tonometry in supine sedated children with glaucoma

AlHarkan

Shamlan

Edward

et al. 2016

Middle East Afr J Ophthalmol

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Purpose:To compare intraocular pressure (IOP) measurements by rebound tonometry (Icare PRO; Icare Finland Oy, Helsinki, Finland) to measurements by indentation tonometry (Pneumotonometer Model 30 classic and Tono-Pen XL; Reichert, Buffalo, NY, USA) in supine sedated children with glaucoma.Methods:Prospective comparative observational study of Saudi Arabian children with glaucoma undergoing chloral hydrate sedation for ophthalmic examination (February 2012 - February 2013). Nonglaucomatous eyes were included as controls. Eyes with corneal scars or prior corneal transplant or lamellar surgery were excluded.Results:Fifty-two eyes (26 OD, 26 OS) of 28 children were included. Thirty-six eyes had glaucoma (32 primary congenital glaucoma, two Sturge-Weber related, and two aphakia related). Sixteen eyes did not have glaucoma (six with pediatric cataract, five normal eyes, two strabismic eyes, two eyes with simple megalocornea, and one eye had peripheral corneal laceration repair. In the glaucoma group, the mean IOP was 17.55 ± 5.97 mmHg (range, 8-31.5 mmHg) with the Icare PRO and 20 ± 6.4 mmHg (range, 8-35.5 mmHg) with the Pneumotonometer from 20.47 ± 6.81 mmHg (range, 10-43 mmHg) with the Tono-Pen XL. The Icare PRO readings were significantly lower than each of the indentation tonometers. For the control group, there was no statistically significant difference in IOP measured by the Icare PRO and the indentation tonometers.Conclusions:In this population of supine sedated children with glaucoma, IOP measurements with the Icare PRO tend to be lower than readings from the Pneumotonometer and Tono-Pen XL.

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Section: Discussioncontrasting

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A comparison of rebound to indentation tonometry in supine sedated children with glaucoma

AlHarkan

Shamlan

Edward

et al. 2016

Middle East Afr J Ophthalmol

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“…With relatively high accuracy, the GAT has become a standard to test the reliability of other tonometers in clinical applications. The iCare RT invented by Kontiola is a new type of portable tonometer, which calculates the tonometer through magnetic induction and records velocity change after the probe strikes the cornea (15–17). The RT measurement shows relatively high accuracy in rats and other animals.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the iCare rebound tonometer and the Goldmann applanation tonometer

Gao

Liu

Zhao

et al. 2017

Experimental and Therapeutic Medicine

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Tonometry is a fundamental procedure in routine ophthalmologic examination. Although regarded as the reference standard, the Goldmann applanation tonometer (GAT) has its limitations. A new portable alternative to the GAT is the iCare rebound tonometer (RT). The aim of the present study was to compare the intraocular pressure (IOP) results obtained using the RT and GAT and then correlate the results with the central corneal thickness (CCT). Moreover, the tolerability and safety of the RT were evaluated. The IOP of 336 patients (672 eyes) was determined by the RT and GAT. The patients were divided into three groups (group A, 7–15 mmHg, n=74; group B, 16–22 mmHg, n=218; and group C, 23–50 mmHg, n=44), based on the GAT IOP readings. Pachymetry and slit lamp inspection were also performed. To establish an agreement between the devices, a Bland-Altman analysis and paired t-test were performed. The correlation between CCT and IOP readings obtained by the two devices were assessed using linear regression correlation analysis. The mean IOP values of the RT and the GAT were 18.30±5.10 and 18.52±4.46 mmHg, respectively. There were no significant differences between them (t=−1.31, P=0.19). The 95% confidence interval of the differences between the two devices was −5.80–6.24 mmHg. The RT readings are correlated well with those of GAT (r=0.806, P=0.001). However, the RT measurements were significantly (t=−2.84, P=0.007) lower (−1.66±3.87 mmHg) than those obtained with GAT when GAT ≥23 mmHg. Both the RT (r=0.390, P=0.001) and the GAT (r=0.191, P=0.001) showed positive correlations with CCT. The IOP measurement with RT was well tolerated. None of the corneal epithelial defects was detected and all subjects denied discomfort. The RT is well tolerated and safe, and can be considered a reliable alternative to GAT for patients in a low to moderate IOP range. However, in patients with high IOP values, the measurements obtained with RT did not correlate well with those obtained by GAT. The RT readings are influenced more by CCT compared to GAT.

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“…The case group received 1 drop of 0.5% timolol without punctal occlusion, twice daily at 8 am and 6 pm. After the instillation, IOP was measured on days 1, 3, 7, 14, 21, and 28 with a Perkins hand-held applanation tonometer (Perkins), in the sitting position [ 16 ]. The IOP daily curve was taken after measurements, and HR of patients was also recorded.…”

Section: Methodsmentioning

confidence: 99%

Roles of CYP2C19 Gene Polymorphisms in Susceptibility to POAG and Individual Differences in Drug Treatment Response

Liu¹,

Jia²,

Wang³

et al. 2016

Med Sci Monit

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BackgroundThe aim of this study was to investigate the roles of cytochrome P450 2C19 (CYP2C19) polymorphisms in primary open-angle glaucoma (POAG) susceptibility and individual responses to drug treatment.Material/MethodsThis case-control study consisted of 93 cases with POAG and 125 controls. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to analyze CYP2C19 single-nucleotide polymorphisms (SNPs). After timolol treatment, patients were classified into side effect (SE) group and non-side effect (NSE) group. According to drug treatment responses, patients were divided into 3 groups: excellent group (Ex) (IOP ≥8 mm Hg); utility group (Ut) (5 0.05). Frequencies of extensive metabolizer phenotype and poor metabolizer phenotype or poor metabolizer phenotype and intermediate metabolizer phenotype were significantly different between the SE group and NSE group (both P<0.05). The distribution of intermediate metabolizer phenotype and extensive metabolizer phenotype were significantly different among Ex group, Ut group, and In group (all P<0.05).ConclusionsWe found no evidence that CYP2C19 polymorphisms are associated with susceptibility to POAG. However, different CYP2C19 metabolizer phenotypes were identified and observed to have important effects on the individual differences in drug treatment response.

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The Icare-Pro Rebound Tonometer Versus the Hand-held Applanation Tonometer in Congenital Glaucoma

Abstract: IOP measurements determined using the new Icare-Pro rebound tonometer showed good correlation with those obtained using the hand-held Perkins applanation tonometer in children with PCG under general anesthesia.

Cited by 26 publications

References 31 publications

A comparison of rebound to indentation tonometry in supine sedated children with glaucoma

A comparison of rebound to indentation tonometry in supine sedated children with glaucoma

Comparison of the iCare rebound tonometer and the Goldmann applanation tonometer

Roles of CYP2C19 Gene Polymorphisms in Susceptibility to POAG and Individual Differences in Drug Treatment Response

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