The IL-6 hypothesis in COVID-19: A phase 2, randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of free IL-6 sequestration by the monoclonal antibody sirukumab in severe and critical COVID-19

Gottlieb, Robert L.; Clement, Meredith; Cook, Paul; Deveikis, Audra; Foong, Kap Sum; Robinson, Philip; Slim, Jihad; Spak, Cedric W.; Buelens, Annemie; Callewaert, Katleen; De Meyer, Sandra; Mo, Wai Ling; Verbrugge, Inge; Van Wesenbeeck, Liesbeth; Zhuang, Yanli; Chien, Jason W.; Opsomer, Magda; Van Landuyt, Erika

doi:10.1016/j.jinf.2024.106241

Journal of Infection

2024

DOI: 10.1016/j.jinf.2024.106241

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The IL-6 hypothesis in COVID-19: A phase 2, randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of free IL-6 sequestration by the monoclonal antibody sirukumab in severe and critical COVID-19

Robert L. Gottlieb,

Meredith Clement,

Paul Cook

et al.

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Pharmacodynamic, prognostic, and predictive biomarkers in severe and critical COVID-19 patients treated with sirukumab

Thys,

Loza,

Lynn

et al. 2024

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Pharmacodynamic, prognostic, and predictive biomarkers in severe and critical COVID-19 patients treated with sirukumab

Thys,

Loza,

Lynn

et al. 2024

Sci Rep

View full text Add to dashboard Cite

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The IL-6 hypothesis in COVID-19: A phase 2, randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of free IL-6 sequestration by the monoclonal antibody sirukumab in severe and critical COVID-19

Cited by 1 publication

References 26 publications

Pharmacodynamic, prognostic, and predictive biomarkers in severe and critical COVID-19 patients treated with sirukumab

Pharmacodynamic, prognostic, and predictive biomarkers in severe and critical COVID-19 patients treated with sirukumab

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