The immunological response toward botulinum toxin in individuals with facial rejuvenation

Chakmakchy, Saygin Abdulkadir; Al-Byti, Aasem Mohamed; Waheeb, Abdulrazzaq Abbas

doi:10.36295/asro.2020.23722

Cited by 1 publication

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“…The present study discovered that the insignificant increase in the IL-17 level could imply the absence of post-injection inflammatory response, which provides insight into the safety of BOTOX, HA filler, and the combination of both. Furthermore, other researchers found that serum IL-2, IL-6, and IL-8 levels, cytokines that promote the production of IL-17, were significantly higher in subjects who received BOTOX injections than in control (33).…”

Section: Discussionmentioning

confidence: 92%

Assessment of selected biochemical and immunological parameters after treatment by Cosmetic Procedures

2023

JPTCP

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Background: The use of non-invasive cosmetic procedures such as Botulinum toxin and hyaluronic acid filler (HA) are commonly used in cosmetic and therapeutic. However, BOTOX therapy is generally considered safe and without significant adverse effects. However, these treatments' impacts must be understood and investigated thoroughly. The objective of this prospective study was to evaluate the impact of using injections of hyaluronic acid filler (HA) and BOTOX on some human biochemical parameters, CBC, and inflammatory markers. Methods: Eighty-five subjects who have undergone BOTOX and/or HA injections were recruited. Samples of study and control groups were collected into EDTA for CBC and serum tubes for the analysis of the rest of the parameters. Results: Our results revealed that using BOTOX and HA filler has no significant effect on ALT, AST, GGT, and CK-MB levels (p-value > 0.05). While there was a decrease in ALP level in subjects injected with both BOTOX and HA filler. Moreover, we discovered that two of our study groups had significantly higher serum LDH levels than the control group. CRP, TNF-α, and IL-17 were elevated in the study group compared with the control group. However, this difference was statistically insignificant (p-value > 0.05). Conclusion: Accordingly, using BOTOX and HA filler may result in mild changes in clinical laboratory tests. Future investigations are now necessary to highlight the influence of these cosmetic procedures on various clinical laboratory parameters.

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Section: Discussionmentioning

confidence: 92%

Assessment of selected biochemical and immunological parameters after treatment by Cosmetic Procedures

2023

JPTCP

View full text Add to dashboard Cite

show abstract

The immunological response toward botulinum toxin in individuals with facial rejuvenation

Cited by 1 publication

References 0 publications

Assessment of selected biochemical and immunological parameters after treatment by Cosmetic Procedures

Assessment of selected biochemical and immunological parameters after treatment by Cosmetic Procedures

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