The Impact of a Regular Blood Donation on the Hematology and EEG of Healthy Young Male Blood Donors

Zhang, Mingxia; Zhang, Gencang; Yang, Jie; Chen, Andrew C. N.

doi:10.1007/s10548-011-0203-0

Cited by 5 publications

(3 citation statements)

References 36 publications

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“…Our previous study showed during blood donation, alpha-1 at the parietalfrontal area on human EEG-DMN transiently with no lasting effect at the post-donation period. 31 In this study, the reverse process of cerebral blood supply did not observe alpha-1 alterations but alpha-2 changes, even alpha-2 did not attain statistical differences. Similar changes existed in delta band spectra, delta intensity was increased in the pre-LVAS group compared with the control group, and the changes were attenuated in the post-LVAS group, which were in accordance with previous cerebral stroke patients EEG alteration.…”

Section: Discussioncontrasting

confidence: 50%

Spectral specific standardized low-resolution brain electromagnetic tomography default mode connectivity network and plasticity alterations in left vertebral artery stent patients

Zhao

et al. 2020

International Journal of Distributed Sensor Networks

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Objective: Vertebral stenting is a valid treatment for posterior stroke. However, the outcome and prognostic factors in the Asian population of vertebral stent are not clear. This study was performed to investigate the quick effect and plasticity alterations of left vertebral artery stenting treatment and to explore the underlying electroencephalogram biomarkers for the prognosis. Method: Electroencephalogram default mode network activity, serum brain-derived neurotrophic factor, and basic neuropsychology estimations were obtained from nine male left vertebral artery stenosis patients who underwent left vertebral artery stenting 24 h before and after left vertebral artery stenting therapy. Result: The beta-1 (13–24 Hz) electroencephalogram field power of the pre–left vertebral artery stenting group was significantly higher compared to that of the post–left vertebral artery stenting and control group ( p < 0.05). The significant different standardized low-resolution brain electromagnetic tomography brain areas of beta-1 band Brodmann areas are 17R, 17L, 18R, 18L, 22R, 22L, 37R, and 37L. The nonliner lag ratio–based functional connectivity analysis showed global increase of connectivity in beta-1 standardized low resolution brain electromagnetic tomography network. Serum brain-derived neurotrophic factor did not show statistically significant changes during groups. Conclusion: Electroencephalogram default mode network provided a functional aspect of left vertebral artery stenting patients, and the beta-1 band power and distribution alterations could be candidate measurements for the plasticity alterations and prognosis evaluation.

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Section: Discussioncontrasting

confidence: 50%

Spectral specific standardized low-resolution brain electromagnetic tomography default mode connectivity network and plasticity alterations in left vertebral artery stent patients

Zhao

et al. 2020

International Journal of Distributed Sensor Networks

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“…After data collection, the EEG was analyzed offline with EEG lab 14.0 software as Zhang et al described[ 20 , 21 ]. Briefly, all EEG data were filtered offline with a 0.5–100 Hz bandpass filter for analysis.…”

Section: Methodsmentioning

confidence: 99%

Different effects of propofol and dexmedetomidine sedation on electroencephalogram patterns: Wakefulness, moderate sedation, deep sedation and recovery

Sun

Pan

et al. 2018

PLoS ONE

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Sedation induces changes in electroencephalography (EEG) dynamics. However, the distinct EEG dynamic characteristics at comparable sedation levels have not been well studied, resulting in potential interpretation errors in EEG monitoring during sedation. We aimed to analyze the EEG dynamics of dexmedetomidine and propofol at comparable sedation levels and to explore EEG changes with increased sedation levels for each agent. We measured the Bispectral Index (BIS) and 20-channel EEG under dexmedetomidine and propofol sedation from wakefulness, moderate sedation, and deep sedation to recovery in healthy volunteers (n = 10) in a randomized, 2-day, crossover study. Observer’s Assessment of Alertness and Sedation (OAA/S) score was used to assess sedation levels. Despite similar changes in increased delta oscillations, multiple differences in the EEG spatiotemporal dynamics were observed between these two agents. During moderate sedation, both dexmedetomidine and propofol induced increased spindle power; however, dexmedetomidine decreased the global alpha/beta/gamma power, whereas propofol decreased the alpha power in the occipital area and increased the global spindle/beta/gamma power. During deep sedation, dexmedetomidine was associated with increased fronto-central spindle power and decreased global alpha/beta/gamma power, but propofol was associated with increased theta/alpha/spindle/beta power, which was maximized in the frontal area. The transition of topographic alpha/spindle/beta power distribution from moderate sedation to deep sedation completely differed between these two agents. Our study demonstrated that there was a distinct hierarchy of EEG changes with increased sedation depths by propofol and dexmedetomidine. Differences in EEG dynamics at the same sedation level might account for differences in the BIS value and reflect the different sedation mechanisms. EEG-based clinical sedation monitoring should consider the effect of drug types on EEG dynamics.

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“…The level of hemoglobin is another reason to consider blood transfusions (1). There is however a risk of misleading results if hemodilution has not yet been completed (9). In these cases, transfusions are not always a straightforward decision.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the diagnostic utility of Glasgow-Blatcford Score, Rockall Score, AIMS65 Score, BUN-to-albumin ratio and BUN-to-creatinine ratio for predicting the need for transfusion in upper gastrointestinal bleeding

2023

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Objective: This study aimed to compare the predictive accuracy of commonly used risk scores in predicting the need for transfusion among patients with upper gastrointestinal bleeding (UGIB). Material and Methods: This retrospective diagnostic utility study was conducted at a tertiary care academic hospital. The primary outcome was the diagnostic accuracy of the Glasgow-Blatchford Score (GBS), the Rockall Score, the AIMS65 Score, the BUN-to-albumin ratio (BAR), and the BUN-to-creatinine ratio (BCR) in the prediction of transfusion in UGIB. Results: Results from the study showed that 75% of the 104 patients included in the study received blood transfusions, with a median of 3 (IQR 2 - 4) units. Admission hemoglobin and hematocrit values were higher in the non-transfusion group (p<0.001 for both comparisons). The GBS (AUC 0.790 [95% CI 0.699 - 0.864]; p<0.001), AIMS65 (AUC 0.672 [95% CI 0.573 - 0.761]; p=0.001), and BAR (AUC 0.625 [95% CI 0.525 - 0.718, p=0.04) were found to be useful diagnostic indices in predicting transfusion administration, with ideal cut-offs of >0, >10.75, and >0, respectively. But Rockall and BCR were not found to be useful diagnostically. The study suggests that these indices can be used as decision tools for transfusion administration in patients with acute upper gastrointestinal bleeding. Conclusion: The GBS demonstrated superior accuracy compared to AIMS65 and BAR, while Rockall score and BCR were found to be ineffective. The GBS may therefore be useful to clinicians when assessing the potential need for blood transfusions in patients with UGIB.

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The Impact of a Regular Blood Donation on the Hematology and EEG of Healthy Young Male Blood Donors

Cited by 5 publications

References 36 publications

Spectral specific standardized low-resolution brain electromagnetic tomography default mode connectivity network and plasticity alterations in left vertebral artery stent patients

Spectral specific standardized low-resolution brain electromagnetic tomography default mode connectivity network and plasticity alterations in left vertebral artery stent patients

Different effects of propofol and dexmedetomidine sedation on electroencephalogram patterns: Wakefulness, moderate sedation, deep sedation and recovery

Analysis of the diagnostic utility of Glasgow-Blatcford Score, Rockall Score, AIMS65 Score, BUN-to-albumin ratio and BUN-to-creatinine ratio for predicting the need for transfusion in upper gastrointestinal bleeding

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