The physical environment of airports plays a crucial role in improving travelers’ perceptions and well-being. Adopting a green physical environment may elicit customers’ cognitive and emotional responses and provide a convenient consumption environment. Brand experience and engagement are other important consumer–firm interactions that influence the attributes of the passengers’ well-being. The current study sought to assess the impact of the eco-design of buildings, brand experience and engagement on the well-being of travelers at an international airport in Saudi Arabia. Additionally, the current study investigated the possible effects of eco-design on airport experience and engagement. The results of the structural equation modeling analysis revealed that the eco-design of airport buildings was independently associated with passengers’ well-being and brand engagement, but not with brand experience. Additionally, well-being was significantly predicted by brand engagement and experience. Airport managers are advised to adopt an internal eco-design to help promote passengers’ connection with the brand and improve their well-being, which would eventually be reflected in their behavioral attributes and decision-making.