The Impact of Antiretroviral Therapy on Mortality in HIV Positive People during Tuberculosis Treatment: A Systematic Review and Meta-Analysis

Odone, Anna; Amadasi, Silvia; White, Richard G.; Cohen, Ted; Grant, Alison D.; Houben, Rein M. G. J.

doi:10.1371/journal.pone.0112017

Cited by 67 publications

(59 citation statements)

References 43 publications

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“…As done before (7), the review was conducted according to the methods recommended by the Cochrane collaboration (8) and the meta-analysis of observational studies in epidemiology (MOOSE) guidelines (9), and documented the process and results in accordance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines (10). …”

Section: Data Sourcesmentioning

confidence: 99%

Bipolar I and II Disorders; A Systematic Review and Meta-Analysis on Differences in Comorbid Obsessive-Compulsive Disorder

Amerio

Stubbs

Odone

et al. 2016

Iran J Psychiatry Behav Sci

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ContextMore than half of the bipolar disorder (BD) cases have an additional diagnosis; one of the most difficult to manage is obsessive-compulsive disorder (OCD). Although some authors recently investigated the co-occurrence of anxiety and BD, the topic remains insufficiently studied. The current study aimed to investigate differences in comorbid OCD between BD-I and BD-II.Evidence AcquisitionA systematic review and meta-analysis was conducted on the prevalence and predictors of comorbid BD-I/BD-II and OCD. Relevant papers published until June 30, 2015 were identified searching the electronic databases MEDLINE, Embase, PsycINFO and the Cochrane Library.ResultsFourteen articles met the inclusion criteria. The pooled prevalence of BD-I in OCD was 3.9% (95% confidence interval (CI), 2.4 to 6.4, I2 = 83%, Q = 56) while that of BD-II in OCD was 13.5% (95% CI, 9.3 to 19.3, I2 = 89%, Q = 91). The pooled prevalence of OCD in BD-I was 21.7 (95% CI, 4.8 to 60.3, I2 = 84%, Q = 95). With regard to OCD-BD predictors, mean age and rate of males did not predict the prevalence of BD-I (β = 0.0731, 95% CI, -0.1097 to 0.256, z = 0.78; β = 0.035, 95% CI, -0.2356 to 0.1656, z = 0.34) and BD-II (β = 0.0577, 95% CI, -0.1942 to 0.0788, z = 0.83; β = -0.0317, 95% CI, -0.1483 to 0.085, z = 0.53) in OCD. The mean age explained some of the observed heterogeneity (R2 = 0.13; R2 = 0.08).ConclusionsThis first systematic review and meta-analysis of the prevalence and predictors of comorbid BD-I/BD-II and OCD suggests that BD-OCD comorbidity is a common condition in psychiatry. However, the available evidence does not allow to assess whether BD-I or BD-II are more common in patients with OCD.

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Section: Data Sourcesmentioning

confidence: 99%

Bipolar I and II Disorders; A Systematic Review and Meta-Analysis on Differences in Comorbid Obsessive-Compulsive Disorder

Amerio

Stubbs

Odone

et al. 2016

Iran J Psychiatry Behav Sci

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“…It is estimated that 86% of PLHIV in SSA know their disease status and are receiving ARV treatment (2, 5, 6). Since 1995, ARV treatment has prevented 7.6 million deaths globally, including 4.8 million deaths in SSA.…”

Section: Introductionmentioning

confidence: 99%

Intimate partner violence and challenges facing women living with HIV/AIDS in accessing antiretroviral treatment at Singida Regional Hospital, central Tanzania

Kosia

Kakoko

Semakafu

et al. 2016

Global Health Action

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BackgroundHuman immunodeficiency virus (HIV) remains a global public health problem. Sub-Saharan Africa is the region most affected by HIV/AIDS in the world. Globally, and in Tanzania in particular, women are more affected by HIV/AIDS than men. Tanzania has been reported to be among the countries with the highest burden of intimate partner violence (IPV). This study explored the challenges facing women living with HIV/AIDS (LWHA) attending the care and treatment clinic (CTC) in Singida Regional Hospital in Tanzania.DesignA qualitative study was performed in which data were collected through in-depth interviews with 35 women LWHA who also experienced IPV. Content analysis was used to analyse the data.ResultsThe study findings showed that women LWHA experienced challenges from their male partners in the form of lack of fare to attend CTC, delayed attendance to CTC, verbal threats and intimidation, mistrust partner resulting in changed antiretroviral (ARV) dosing time. Also, systemic challenges such as malfunction of CD4 count testing apparatus contributed to mistrust from their male partners which led to IPV.ConclusionIn this study, women LWHA experienced IPV challenges that resulted in poor adherence to ARV medication and CTC attendance, as well as insufficient time to collect ARV medication. It is recommended that the government address systemic challenges faced by women LWHA, introduce multiple approaches to address the needs of women LWHA experiencing IPV, and develop strong policies to prevent IPV against women in Tanzania, regardless of their HIV status.

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“…Importantly, it is possible to mitigate the risks of poor outcomes associated with many of these conditions. Antiretroviral therapy lowers the risk of death in TB patients with HIV by nearly 60% . Better diabetes management improves TB treatment outcomes .…”

Section: Discussionmentioning

confidence: 99%

Addressing tuberculosis patients’ medical and socio‐economic needs: a comprehensive programmatic approach

Contreras

Millones

Cruz

et al. 2017

Tropical Med Int Health

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The Impact of Antiretroviral Therapy on Mortality in HIV Positive People during Tuberculosis Treatment: A Systematic Review and Meta-Analysis

Cited by 67 publications

References 43 publications

Bipolar I and II Disorders; A Systematic Review and Meta-Analysis on Differences in Comorbid Obsessive-Compulsive Disorder

Bipolar I and II Disorders; A Systematic Review and Meta-Analysis on Differences in Comorbid Obsessive-Compulsive Disorder

Intimate partner violence and challenges facing women living with HIV/AIDS in accessing antiretroviral treatment at Singida Regional Hospital, central Tanzania

Addressing tuberculosis patients’ medical and socio‐economic needs: a comprehensive programmatic approach

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