The impact of aspirin on Klebsiella pneumoniae liver abscess in diabetic patients

Tai, Chien-Hsiang; Hsu, Chien‐Ning; Yang, Shih‐Cheng; Wu, Cheng‐Kun; Liang, Chih‐Ming; Tai, Wei‐Chen; Chuah, Seng‐Kee; Lee, Chen‐Hsiang

doi:10.1038/s41598-020-78442-8

Cited by 4 publications

(3 citation statements)

References 38 publications

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“…Liu et al identified 5912 patients with PLA and evaluated recurrence PLA rates between ASA users and non-users, which were 42.5 and 74.6 per 1000 person-years of follow-up, respectively [ 77 ]. Similar findings were reported in a large cohort of diabetic patients, with ASA continuous intake for >90 days associated with a lower risk of PLA [ 78 ].…”

Section: Resultssupporting

confidence: 89%

Aspirin and Infection: A Narrative Review

et al. 2022

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Acetylsalicylic acid (ASA) is one of the most commonly used drugs in the world. It derives from the extract of white willow bark, whose therapeutic potential was known in Egypt since 1534 BC. ASA’s pharmacological effects are historically considered secondary to its anti-inflammatory, platelet-inhibiting properties; however, human studies demonstrating a pro-inflammatory effect of ASA exist. It is likely that we are aware of only part of ASA’s mechanisms of action; moreover, the clinical effect is largely dependent on dosages. During the past few decades, evidence of the anti-infective properties of ASA has emerged. We performed a review of such research in order to provide a comprehensive overview of ASA and viral, bacterial, fungal and parasitic infections, as well as ASA’s antibiofilm properties.

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Section: Resultssupporting

confidence: 89%

Aspirin and Infection: A Narrative Review

et al. 2022

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“…However, rarely, it can also cause infections in other organ systems such as in the gastrointestinal tract, meninges, eyes, and ears. Most commonly, K. pneumoniae causes infection in alcoholic patients and those with diabetes, especially if uncontrolled, which was recently reported in at least three case reports linking diabetes and hepatic abscesses [ 1 , 8 , 9 ], and at least one case report linking diabetes and biliary abscesses [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

Emerging Multiorgan Klebsiella pneumoniae Invasive Syndrome Leading to Septic Shock: A Case Report and Review of the Literature

Villanueva¹,

Taunk²,

Padmanabhan³

et al. 2022

Cureus

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Klebsiella pneumoniae (K. pneumoniae) is a community-acquired pathogen that typically causes pneumonia and urinary tract infections. Rarely, it can affect other organ systems such as the gastrointestinal tract, as well as the meninges, ears, eyes, and spine. We present the case of a 62-year-old male admitted with septic shock secondary to necrotizing pneumonia and multiple hepatic liver abscesses, which to the best of our knowledge, is the first reported case of multiorgan invasive K. pneumoniae infection, including the presence of a newly recognized syndrome referred as Invasive Liver Abscess Syndrome (ILAS). It is important to maintain both ILAS and K. pneumoniae invasive syndrome (KPIS) in the differential diagnosis, especially in areas of the world with a large number of tourists and immigrants, such as New York City, where the presented case took place.

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“…Although the population size is smaller than that of the NHI database, the CGRD contains more clinical information (laboratory results, examination and pathological reports, medical and nursing records) than the NHI database. To date, CGRD has been widely used to establish real-world evidence studies in many fields [ [3] , [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] ]. However, previous studies pointed out that selection bias and loss of follow-up were two major limitations of CGRD [ 2 , 4 , 5 , 8 , 16 ].…”

mentioning

confidence: 99%