The impact of autoimmune thyroid disease on the course of myasthenia gravis

Gender and quality of life in myasthenia gravis patients from the myasthenia gravis foundation of America registry

“…27,28 A greater prevalence of other autoimmune diseases among MG has been well described. [27][28][29][30][31][32] Autoimmune thyroid disease, systemic lupus erythematosus, and inflammatory bowel disease were more common in women, whereas type 1 diabetes mellitus and psoriasis were not, which is also consistent with the literature. [27][28][29][30][31][32] Depression and anxiety were more common in women, which would be expected to adversely affect QOL.…”

“…Autoimmune and treatment related comorbidities were commonly reported in this population, consistent with previous reports. [11][12][13][14][15] What makes the treatment of MG more difficult in women? There are several possible explanations: MG may be a more severe condition for women; there may be different efficacies of therapeutic modalities between men, and treatment biases may exist, resulting in different treatment of men and women; women with more poorly controlled disease may be more apt to enter a registry; men may underreport their disease severity.…”

Treatment outcome in juvenile‐onset myasthenia gravis

“…In our earlier study, MG accompanied by autoimmune thyroid disease had a milder course than MG alone. 21 Ocular symptoms could not be attributed to thyroid disease in any of our patients.…”

“…The presence of concomitant diseases and MG is common, both in children and adults. 15,21,22 It is of interest that such association does not worsen the prognosis. In our cohort, thyroid diseases were most common as previously reported.…”