The impact of bilateral stone disease on patients’ disease progression and quality of life

Raizenne, B.L.; Deyirmendjian, C.; Lafontaine, M-L.; Balde, M.; Bechis, S.; Sur, R.; Nakada, S.; Antonelli, J.; Streeper, N.; Sivalingam, S.; Viprakasit, D.; Averch, T.; Landman, J.; Chi, T.; Pais, V.; Chew, B.; Bird, V.; Andonian, S.; Canvasser, N.; Harper, J.; Bhojani, N.

doi:10.1016/s0302-2838(23)00412-8

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“…This cycle of recurrence necessitates frequent medical interventions and long-term treatment strategies, substantially increasing the financial burden on patients. Moreover, these recurring conditions might culminate in chronic pain and renal impairment, exacerbating the patient's overall health status [25]. The psychological impact of recurrent kidney stones is profound, as it escalates stress levels and emotional burdens, adversely affecting mental health and wellbeing [26].…”

Section: Discussionmentioning

confidence: 99%

Clinical efficacy and short-term outcome of combining flexible cystoscopy with percutaneous nephrolithotomy for complex renal stone management

Zhao

2024

Am J Transl Res

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Objective: This study aims to evaluate the clinical efficacy and short-term prognosis of using flexible cystoscopy with percutaneous nephrolithotomy to treat complex renal stones. Methods: A retrospective analysis was conducted on patients with complex kidney stones treated at Gansu Provincial Hospital of TCM and Lanzhou City No. 2 People's Hospital from July 2019 to July 2022. The study divided the patients into a control group (n=95), who underwent percutaneous nephrolithotomy alone, and an observation group (n=109), who received additional holmium laser lithotripsy and cystoscopy. We compared stone clearance rates at 5 days and 1 month post-surgery, analyzed patient prognosis over a year based on stone recurrence, and assessed risk factors through logistic regression. Perioperative data, changes in renal function indiex 3 days post-surgery, and complication rates were also evaluated. Results: The observation group exhibited a significantly higher stone clearance rate at 5 days post-surgery (P=0.002) compared to the control group, although no significant difference was observed at 1 month (P=0.823). The operative time was significantly shorter (P<0.001), and postoperative levels of BUA, Cys-c, and β2-BMG were lower (P<0.05) in the observation group. Additionally, treatment regimen, BMI, and STONE score were influencing factors for stone recurrence within 1 year. Conclusion: Flexible cystoscopy combined with percutaneous nephrolithotomy offers superior short-term outcomes in the treatment of complex renal stones, including enhanced stone clearance, reduced operative time, and minimized renal function impairment shortly after surgery. Moreover, treatment approach, BMI, and STONE score play pivotal roles in predicting stone recurrence.

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Section: Discussionmentioning

confidence: 99%

Clinical efficacy and short-term outcome of combining flexible cystoscopy with percutaneous nephrolithotomy for complex renal stone management

Zhao

2024

Am J Transl Res

View full text Add to dashboard Cite

show abstract

The impact of bilateral stone disease on patients’ disease progression and quality of life

Cited by 1 publication

References 0 publications

Clinical efficacy and short-term outcome of combining flexible cystoscopy with percutaneous nephrolithotomy for complex renal stone management

Clinical efficacy and short-term outcome of combining flexible cystoscopy with percutaneous nephrolithotomy for complex renal stone management

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