The impact of body mass index on post resuscitation survival after cardiac arrest: A meta-analysis

Kakavas, Sotirios; Georgiopoulos, Georgios; Oikonomou, Dimitrios; Karayiannis, Dimitrios; Masi, Stefano; Karlis, George; Xanthos, Theodoros

doi:10.1016/j.clnesp.2018.01.071

Cited by 19 publications

(13 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A recent meta-analysis showed that the hospital survival rate was lower in the underweight group and higher in the overweight group, but no difference was found on a subgroup analysis of patients who experienced OHCA only [21]. Moreover, another meta-analysis found that overweight patients had better survival and neurologic outcomes after cardiac arrest, and it was amplified in the IHCA with TTM group [17]. However, these meta-analyses did not reflect confounding factors, and the result was different according to the included studies.…”

Section: Discussionmentioning

confidence: 99%

“…A large, multicentre, prospective study with data from a national registry showed that the BMI groups had similar rates of survival, except underweight patients with IHCA caused by non-shockable rhythm [16]. A meta-analysis that evaluated the effect of BMI on survival post resuscitation showed that overweight patients had a favourable outcome considering both survival and neurologic outcomes, especially in patients who experienced IHCA and patients without therapeutic hypothermia [17].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Association between the body mass index and outcomes of patients resuscitated from out-of-hospital cardiac arrest: a prospective multicentre registry study

Lee

Kang

et al. 2021

Scand J Trauma Resusc Emerg Med

View full text Add to dashboard Cite

Background The effects of the body mass index (BMI) on outcomes of patients resuscitated from cardiac arrest are controversial. Therefore, the current study investigated the association between the BMI and the favourable neurologic outcomes and survival to discharge of patients resuscitated from out-of-hospital cardiac arrest (OHCA). Methods This multicentre, prospective, nationwide OHCA registry-based study was conducted using data from the Korean Cardiac Arrest Resuscitation Consortium (KoCARC). We enrolled hospitals willing to collect patient height and weight and included patients who survived to the hospital between October 2015 and June 2018. The included patients were categorised into the underweight (< 18.5 kg/m2), normal weight (≥18.5 to < 25 kg/m2), overweight (≥25 to < 30 kg/m2), and obese groups (≥30 kg/m2) according to the BMI per the World Health Organization (WHO) criteria. The primary outcome was a favourable neurologic outcome; the secondary outcome was survival to discharge. Univariate and multivariate analyses were performed to investigate the association between BMI and outcomes. Results Nine hospitals were enrolled; finally, 605 patients were included in our analysis and categorised per the WHO BMI classification. Favourable neurologic outcomes were less frequent in the underweight BMI group than in the other groups (p = 0.002); survival to discharge was not significantly different among the BMI groups (p = 0.110). However, the BMI classification was not associated with favourable neurologic outcomes or survival to discharge after adjustment in the multivariate model. Conclusion The BMI was not independently associated with favourable neurologic and survival outcomes of patients surviving from OHCA.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Association between the body mass index and outcomes of patients resuscitated from out-of-hospital cardiac arrest: a prospective multicentre registry study

Lee

Kang

et al. 2021

Scand J Trauma Resusc Emerg Med

View full text Add to dashboard Cite

show abstract

“…März 2020 unter Verwendung der Schlüsselwörter „Fettleibigkeit“ UND „Kreislaufstillstand oder Kreislaufstillstand“ ODER „Wiederbelebung oder kardiopulmonale Wiederbelebung“ in den letzten 5 Jahren durchgeführt ( n = 122). Es wurden zwei Metaanalysen zum Zusammenhang zwischen BMI und Ergebnis nach Kreislaufstillstand veröffentlicht [ 607 , 608 ]. Die Modifikation der Thoraxkompression basiert auf einer retrospektiven Studie zur Bewertung der Thoraxkompressionstiefe bei adipösen Patienten mithilfe der Computertomographie (CT; [ 609 ]).…”

Section: Evidenz Die In Die Leitlinien Einfließtunclassified

Kreislaufstillstand unter besonderen Umständen

Lott

Truhlář

Alfonzo

et al. 2021

Notfall Rettungsmed

View full text Add to dashboard Cite

Diese Leitlinien des European Resuscitation Council (ERC) für den Kreislaufstillstand unter besonderen Umständen basieren auf dem 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. Dieses Kapitel enthält Leitlinien zu den Modifikationen der lebensrettenden Basismaßnahmen und erweiterten lebensrettenden Maßnahmen zur Vorbeugung und Behandlung von Kreislaufstillständen unter besonderen Umständen; insbesondere spezielle Ursachen (Hypoxie, Trauma, Anaphylaxie, Sepsis, Hypo‑/Hyperkaliämie und andere Elektrolytstörungen, Hypothermie, Lawinengeschehen, Hyperthermie und maligne Hyperthermie, Lungenembolie, Koronarthrombose, Herzbeuteltamponade, Spannungspneumothorax, Giftstoffe), spezielle Umstände (Operationssaal, Herzchirurgie, Herzkatheterlabor, Dialyseeinheit, Zahnkliniken, Transport während des Flugs, Kreuzfahrtschiffe, Sport, Ertrinken, Großschadensereignisse) und spezielle Patientengruppen (Asthma und chronisch obstruktive Lungenerkrankung, neurologische Erkrankungen, krankhafte Adipositas, Schwangerschaft). Zusatzmaterial online Die Online-Version dieses Beitrags (10.1007/s10049-021-00891-z) enthält das originale Zusatzmaterial aus dem Artikel in Resuscitation. Beitrag und Zusatzmaterial stehen Ihnen auf www.springermedizin.de zur Verfügung. Bitte geben Sie dort den Beitragstitel in die Suche ein, das Zusatzmaterial finden Sie beim Beitrag unter „Ergänzende Inhalte“.

show abstract

“…The overall survival condition and neurological prognosis of overweight or obese patients were superior to those of normal-weight patients because overweight or obese patients may have greater metabolic reserves in critical life-threatening scenarios 9 , 11 – 13 . However, two recent meta-analyses have shown that survival rates and neurological outcomes did not differ significantly between obese and non-obese patients 6 , 14 .…”

Section: Introductionmentioning

confidence: 95%

“…Because patients with cardiogenic arrest are relatively young, mortality and unsatisfactory prognosis among these patients cause a considerable economic and social burden 5 . Cardiogenic arrest may be caused by CAD, acute myocardial infarction, heart failure, cardiac tamponade, or fatal arrhythmia 5 , 6 , which have been reported to be attributed to obesity. Obesity was also reported to increase the risk of sudden arrhythmic death syndrome and left ventricular hypertrophy 7 .…”

Section: Introductionmentioning

confidence: 99%

Obese cardiogenic arrest survivors with significant coronary artery disease had worse in-hospital mortality and neurological outcomes

Sung

Chen

Chang

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Cardiogenic arrest is the major cause of sudden cardiac arrest (SCA), accounting for 20% of all deaths annually. The association between obesity and outcomes in cardiac arrest survivors is debatable. However, the effect of obesity on the prognosis of patients with significant coronary artery disease (CAD) successfully resuscitated from cardiogenic arrest is unclear. Thus, the association between body mass index (BMI) and outcomes in cardiogenic arrest survivors with significant CAD was investigated. This multicentre retrospective cohort study recruited 201 patients from January 2011 to September 2017. The eligible cardiogenic arrest survivors were non-traumatic adults who had undergone emergency coronary angiography after sustained return of spontaneous circulation and had significant coronary artery stenosis. BMI was used to classify the patients into underweight, normal-weight, overweight, and obese groups (< 18.5, 18.5–24.9, 25.0–29.9, and ≥ 30 kg/m2; n = 9, 87, 72, and 33, respectively). In-hospital mortality and unsatisfactory neurological outcomes (cerebral performance scale scores = 3–5) were compared among the groups. The obese group presented higher in-hospital mortality and unsatisfactory neurological outcome risks than the normal-weight group (in-hospital mortality: adjusted hazard ratio = 4.27, 95% confidence interval (CI) 1.87–12.04, P = 0.008; unsatisfactory neurological outcomes: adjusted odds ratio = 3.33, 95% CI 1.42–8.78, P = 0.009). Subgroup analysis showed significantly higher in-hospital mortality in the obese patients than in the others in each clinical characteristic. In cardiogenic arrest survivors with significant CAD, obesity was associated with high risks of mortality and unsatisfactory neurological recovery.

show abstract

The impact of body mass index on post resuscitation survival after cardiac arrest: A meta-analysis

Cited by 19 publications

References 52 publications

Association between the body mass index and outcomes of patients resuscitated from out-of-hospital cardiac arrest: a prospective multicentre registry study

Association between the body mass index and outcomes of patients resuscitated from out-of-hospital cardiac arrest: a prospective multicentre registry study

Kreislaufstillstand unter besonderen Umständen

Obese cardiogenic arrest survivors with significant coronary artery disease had worse in-hospital mortality and neurological outcomes

Contact Info

Product

Resources

About