The impact of chronic urticaria on the quality of life

O'Donnell, B; Lawlor, Frances; SIMPSON, J.; Morgan, Myfanwy; Greaves, Malcolm W.

doi:10.1046/j.1365-2133.1997.d01-1168.x

Cited by 360 publications

(345 citation statements)

References 20 publications

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“…The extent of HRQoL impairment has been shown to be comparable with that of patients suffering from severe ischemic heart disease [8] and to be one of the highest among dermatologic disorders [23]. A recent GA 2 LEN position paper recommended the use of evidence-based patient-reported outcome instruments, including HRQoL and disease activity measures, in clinical trials with urticaria patients [24].…”

Section: Discussionmentioning

confidence: 99%

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Disease Activity Only Moderately Correlates with Quality of Life Impairment in Patients with Chronic Spontaneous Urticaria

Koti¹,

Weller²,

Makris³

et al. 2013

Dermatology

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Background: The impact of chronic spontaneous urticaria (CSU) on health-related quality of life (HRQoL) is widely held to be mainly influenced by disease activity and comorbidities. Objective: To assess the correlation between disease activity and HRQoL impairment by using validated disease-specific instruments. Methods: The Chronic Urticaria Quality of Life Questionnaire (CU-Q₂oL) was translated into Greek and subsequently applied to 110 CSU patients along with the Dermatology Life Quality Index and the Urticaria Activity Score. After the validity and reliability of the Greek CU-Q₂oL had been determined, we assessed the relation between disease activity and HRQoL impairment by computing correlations as well as by performing multiple regression analysis. Results: Exploratory factor analysis revealed a six-scale structure of the Greek CU-Q₂oL that explained 67.9% of its total variance. The internal consistency was satisfactory with Cronbach's α >0.7. Disease activity was the only predictor of quality of life impairment, but it only moderately correlated with the CU-Q₂oL total score (r = 0.40, p < 0.0001). Conclusion: Our results suggest that there are additional factors to disease activity that are responsible for the pronounced reduction of HRQoL in CSU, and this supports the recommendation to assess and monitor both disease activity and quality of life in CSU patients.

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Section: Discussionmentioning

confidence: 99%

“…The reason for this substantial HRQoL impairment is usually attributed to disease activity and comorbidities [8,9,10]. However, as of yet, there are only limited data to prove this.…”

Section: Introductionmentioning

confidence: 99%

Disease Activity Only Moderately Correlates with Quality of Life Impairment in Patients with Chronic Spontaneous Urticaria

Koti¹,

Weller²,

Makris³

et al. 2013

Dermatology

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“…The impact of CU on the QoL of patients has been reported to be comparable with the impact of severe coronary artery disease [3]. Furthermore, while CU is a self-limited disease with a mean duration of 2-5 years, 20% of patients suffer from long-lasting CU [2], which may last for more than 20 years [4]. …”

Section: Introductionmentioning

confidence: 92%

An Observational Study of the Diagnosis and Management of Chronic Urticaria in the UK

Ardern‐Jones

Eren

et al. 2015

Int Arch Allergy Immunol

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Background: Patients with chronic urticaria (CU) in the UK could be referred to health care professionals (HCPs) with diverse specialties using different guidelines. The aims of the present study were to determine which CU guidelines HCPs in the UK use, which tests they use for the diagnosis of CU, and how they manage CU. Methods: In this UK-wide survey, we designed a questionnaire covering the diagnosis and management of CU based on current guidelines. The link to the questionnaire was sent to the British Society for Allergy and Clinical Immunology (BSACI), the British Association of Dermatologists (BAD), the British Society of Immunology (BSI), and the Food Allergy and Intolerance Specialist Group (FAISG) of the British Dietetic Association (BDA), who distributed the link to their members. Results: The questionnaire was completed by 55 allergists/immunologists, 64 dermatologists, and 43 dietitians. More dermatologists used the BAD guidelines in comparison with allergists and immunologists (93.6 vs. 12.5%; p < 0.001). On the other hand, the BSACI guidelines (83.3 vs. 14.9%; p < 0.001) and the European Academy of Allergy and Clinical Immunology (EAACI)/Global Allergy and Asthma European Network (GA²LEN)/European Dermatology Forum (EDF)/World Allergy Organization (WAO) guidelines (2013) (52.1 vs. 10.6%; p < 0.001) were used by more allergists and immunologists compared to dermatologists. Differences were found between allergists/immunologists and dermatologists with regard to guidelines used, investigations performed, preference of first-line antihistamine, and prescription of alternative treatment methods. Conclusion: In conclusion, differences in the diagnosis and management of CU between HCPs of diverse specialties were identified, which reflected differences among the guidelines used.

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“…40 Los pacientes con UC tienen puntuaciones más altas en el Índice de depresión de Beck e índice de ansiedad de Beck. 41 La reducción de la productividad laboral es causada por la interferencia del sueño. 42 • Problemas gastrointestinales: los pacientes con síntomas de dispepsia deben someterse a una prueba de rutina para detectar Helicobacter pylori.…”

Section: • Enfermedades Psicosomáticas Y Psiquiátricasunclassified

“…Las lesiones se extienden sobre el abdomen. 41 • Hábito de fumar: agentes como el tabaco (especialmente el uso de tabaco perfumado) y la Cannabis pueden agravar la urticaria crónica.…”

Section: • Enfermedades Psicosomáticas Y Psiquiátricasunclassified

¿Es posible simplificar el abordaje diagnóstico de urticaria crónica? Una lista de verificación de información clínica

Chérrez-Ojeda

Robles‐Velasco

Bedoya-Riofrio

et al. 2017

RAM

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Background: Existing clinical guidelines do not offer an efficient alternative for the collection of data on relevant clinical traits during history and physical of the patient with chronic urticaria. Objective: Our aim was to provide a clinical data checklist together with its guide to allow for thorough information to be obtained and for a physical exam that identifies the main features and triggering factors of the disease to be carried out. Methods: A search was conducted for relevant literature on chronic urticaria in Medline, the Cochrane library and PubMed. Results: We developed an easy-to-use clinical data checklist with its corresponding clinical guide, comprised by 42 items based on two components: essential clues for history taking and chronic urticaria diagnosis (typical symptoms according to subgroups, etiology and laboratory results). Some components are the time of disease onset, wheals' duration, shape, size, color and distribution, associated angioedema, atopy, triggering factors and others. Conclusions: The clinical data checklist and its guide constitute a tool to focus, guide and save time in medical consultation, with the main purpose to aid physicians in providing better diagnosis and management of the disease.

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The impact of chronic urticaria on the quality of life

Cited by 360 publications

References 20 publications

Disease Activity Only Moderately Correlates with Quality of Life Impairment in Patients with Chronic Spontaneous Urticaria

Disease Activity Only Moderately Correlates with Quality of Life Impairment in Patients with Chronic Spontaneous Urticaria

An Observational Study of the Diagnosis and Management of Chronic Urticaria in the UK

¿Es posible simplificar el abordaje diagnóstico de urticaria crónica? Una lista de verificación de información clínica

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